ArticleAntioxidants (Basel, Switzerland)2021
Dietary Vitamin C and Vitamin C Derived from Vegetables Are Inversely Associated with the Risk of Depressive Symptoms among the General Population.
Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Associations of Dietary Vitamin C and E Intake With Depression. A Meta-Analysis of Observational Studies.Frontiers in nutrition · 2022Pooled it
- Association between oxidative balance score and psychological disorders in adults.Scientific reports · 2026Article
- Examining the association between the Mediterranean diet and depression: a cross-sectional study in Lebanon.Frontiers in nutrition · 2025Article
- The association of vitamin deficiency with depression risk in late-life depression: a review.Frontiers in nutrition · 2025Review
- The Risk of Depressive Symptoms according to the Dietary Intake of Vitamin C.Neuropsychobiology · 2025Article
- Exploring the Relationship Between Dietary Habits and Perceptions of Mental and Physical Disorders, or a Sense of Accomplishment in Japan.Nutrients · 2024Article
- Association of dietary antioxidant intake with depression risk and all-cause mortality in people with prediabetes.Scientific reports · 2024Article
- Association between 29 food groups of diet quality questionnaire and perceived stress in Chinese adults: a prospective study from China health and nutrition survey.BMC public health · 2024Article
- Associations of vegetable and fruit intake, physical activity, and school bullying with depressive symptoms in secondary school students: the mediating role of internet addiction.BMC psychiatry · 2024Article
- Smartphone survey data reveal the timecourse of changes in mood outcomes following vitamin C or kiwifruit intervention in adults with low vitamin C.The British journal of nutrition · 2024Article
- Higher serum ascorbic acid levels are associated with lower depression prevalence in US adults: a case-control study.Frontiers in nutrition · 2024Article
- Process optimisation for enzymatic clarification of indigenous wild watermelon (Food science and technology international = Ciencia y tecnologia de los alimentos internacional · 2023Article
- Association of Urinary Iodine Concentration with Depressive Symptoms among Adults: NHANES 2007-2018.Nutrients · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin C is a water-soluble antioxidant. Reducing the level of oxidative stress can alleviate depression. Therefore, we investigated the correlation between dietary vitamin C intake and the risk of depressive symptoms in the general population. Data from the 2007-2018 National Health and Nutrition Examination Survey were used in our study. The dietary intake of vitamin C was assessed by two 24-h dietary recalls. Depressive symptoms were assessed with the Patient Health Questionnaire-9. Logistic regression and restricted cubic spline models were applied to assess the relationship between dietary vitamin C intake and the risk of depressive symptoms. The multivariate adjusted odds ratio (95% confidence interval) of depressive symptoms for the highest vs. lowest category of dietary vitamin C intake and vitamin C intake derived from vegetables were 0.73 (0.58-0.91) and 0.73 (0.56-0.95). In subgroup analyses, dietary vitamin C intake was negatively correlated with the risk of depressive symptoms in females 18-39 years old and 40-59 year-old groups. A dose-response analysis showed that there was a nonlinear relationship between dietary vitamin C intake and the risk of depressive symptoms. Dietary vitamin C intake and vitamin C intake derived from vegetables were inversely associated with the risk of depressive symptoms among the general population. We recommend increasing the intake of vegetables in daily diet.
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