Evidence map›Paper›PMID 34943085›Full record

ArticleAntioxidants (Basel, Switzerland)2021

A Pilot Study on the

Domitilla Vanni, Nicola Viceconte, Greta Petrella, Flavio Giuseppe Biccirè, Francesco Pelliccia, Gaetano Tanzilli, Daniel Oscar Cicero

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Biomarkers of Oxidative Stress in Acute and Chronic Diseases.Antioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Domitilla VanniDepartment of Chemical Science and Technology, University of Rome "Tor Vergata", 00133 Rome, Italy.
Nicola ViceconteDepartment of Internal Medicine, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Policlinic Umberto I, 00161 Rome, Italy.ORCID 0000-0002-4963-005X
Greta PetrellaDepartment of Chemical Science and Technology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-9449-9820
Flavio Giuseppe BiccirèDepartment of Internal Medicine, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Policlinic Umberto I, 00161 Rome, Italy.
Francesco PellicciaDepartment of Internal Medicine, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Policlinic Umberto I, 00161 Rome, Italy.ORCID 0000-0003-1260-1308
Gaetano TanzilliDepartment of Internal Medicine, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Policlinic Umberto I, 00161 Rome, Italy.
Daniel Oscar CiceroDepartment of Chemical Science and Technology, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0001-5012-1714
Policlinico Umberto I · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takotsubo syndrome (TTS) presents as an acute coronary syndrome characterized by severe left ventricular (LV) dysfunction and non-obstructive coronary artery disease that typically shows spontaneous recovery within days or weeks. The mechanisms behind TTS are mainly related to beta-adrenergic overstimulation and acute endogenous catecholamine surge, both of which could increase oxidative status that may induce further deterioration of cardiac function. Although several studies reported evidence of inflammation and oxidative stress overload in myocardial tissue of TTS models, systemic biochemical evidence of augmented oxidant activity in patients with TTS is lacking. In this study, serum samples of ten TTS patients and ten controls have been analyzed using

Indexed as

1H-NMRmetabolomicssystemic stressor responseTakotsubo syndrome

Identifiers

PMID34943085
PMCPMC8750825
OpenAlexW4200377949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.