Evidence map›Paper›PMID 34943082›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Parenteral Antioxidant Supplementation at Birth Improves the Response to Intranasal Vaccination in Newborn Dairy Calves.

Arpita Nayak, Angel Abuelo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Genomic and phenotypic analysis ofFrontiers in microbiology · 2026
    Article
  2. Zinc about it - zinc and calf immunity.Frontiers in immunology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arpita NayakDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, 736 Wilson Rd., East Lansing, MI 48824, USA.ORCID 0000-0001-5548-117X
Angel AbueloDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, 736 Wilson Rd., East Lansing, MI 48824, USA.ORCID 0000-0001-9734-0148

Funding

Michigan Alliance for Animal Agriculture n/aMichigan Animal Health Foundation N/ANIH HHS 5T35OD016477-19United States Department of Agriculture Animal Health project 1016161
6 · The paper itself

Abstract

Newborn calves experience oxidative stress throughout the first month of their life, which is known to decrease lymphocyte functions relevant to vaccine responsiveness. Thus, this study aimed to determine the extent to which parenteral antioxidant supplementation given at birth improves the response to an intranasal viral vaccine in the first month of life of newborn dairy calves. For this, 21 calves were randomly assigned at birth to one of two commercially available antioxidant micronutrient supplements or a placebo group receiving 0.9% sterile saline (

Indexed as

dairy cattlemicronutrientsmucosal immunityoxidative stress

Identifiers

PMID34943082
PMCPMC8750176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.