Evidence map›Paper›PMID 34943064›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Formation of Cyclobutane Pyrimidine Dimers after UVA Exposure (Dark-CPDs) Is Inhibited by an Hydrophilic Extract of

Mikel Portillo-Esnaola, Azahara Rodríguez-Luna, Jimena Nicolás-Morala, María Gallego-Rentero, María Villalba, Ángeles Juarranz, Salvador González

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Research progress in the role of ultraviolet in the pathogenesis of rosacea.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  5. Review
  6. Article
  7. Ultraviolet Radiation Biological and Medical Implications.Current issues in molecular biology · 2024
    Review
  8. Clinical Applications ofLife (Basel, Switzerland) · 2023
    Review
  9. Uses ofJournal of clinical medicine · 2023
    Article
  10. Article
  11. Protective Effect of the Hydrophilic Extract ofAntioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mikel Portillo-EsnaolaDepartment of Biology, Faculty of Sciences, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Autónoma University of Madrid (UAM), 28049 Madrid, Spain.ORCID 0000-0003-0830-7237
Azahara Rodríguez-LunaCantabria Labs, Innovation and Development, 28043 Madrid, Spain.ORCID 0000-0002-1529-7674
Jimena Nicolás-MoralaDepartment of Biology, Faculty of Sciences, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Autónoma University of Madrid (UAM), 28049 Madrid, Spain.
María Gallego-RenteroDepartment of Biology, Faculty of Sciences, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Autónoma University of Madrid (UAM), 28049 Madrid, Spain.
María VillalbaCantabria Labs, Medical Affairs Department, 28043 Madrid, Spain.
Ángeles JuarranzDepartment of Biology, Faculty of Sciences, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Autónoma University of Madrid (UAM), 28049 Madrid, Spain.ORCID 0000-0002-6574-2887
Salvador GonzálezDepartment of Medicine and Medical Specialties, Alcalá de Henares University, 28805 Madrid, Spain.ORCID 0000-0001-9282-4784
Instituto Ramón y Cajal de Investigación Sanitaria · ESUniversidad de Alcalá · ESUniversidad de Cantabria · ES

Funding

Instituto de Salud Carlos III PI18/00708
6 · The paper itself

Abstract

Exposure to sun and especially to ultraviolet radiation (UVR) exerts well known detrimental effects on skin which are implicated in malignancy. UVR induces production of cyclobutane pyrimidine dimers (CPDs), immediately during exposure and even hours after the exposure, these latter being called dark-CPDs, as consequence of the effects of different reactive species that are formed. Fernblock

Indexed as

cyclobutane pyrimidine dimersdark cyclobutene pyrimidine dimersmelanocytesphotoprotectionPolypodium leucotomosskin cancerultraviolet radiation

Identifiers

PMID34943064
PMCPMC8750109
OpenAlexW4200348213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.