Evidence map›Paper›PMID 34942990›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Regioselective and Stereoselective Epoxidation of n-3 and n-6 Fatty Acids by Fungal Peroxygenases.

Alejandro González-Benjumea, Dolores Linde, Juan Carro, René Ullrich, Martin Hofrichter, Angel T Martínez, Ana Gutiérrez

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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  6. EngineeringAntioxidants (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alejandro González-BenjumeaInstituto de Recursos Naturales y Agrobiología de Sevilla (IRNAS), Consejo Superior de Investigaciones Científicas (CSIC), Reina Mercedes 10, E-41012 Seville, Spain.ORCID 0000-0003-2857-9491
Dolores LindeCentro de Investigaciones Biológicas "Margarita Salas" (CIB), Consejo Superior de Investigaciones Científicas (CSIC), Ramiro de Maeztu 9, E-28040 Madrid, Spain.ORCID 0000-0002-0359-0566
Juan CarroCentro de Investigaciones Biológicas "Margarita Salas" (CIB), Consejo Superior de Investigaciones Científicas (CSIC), Ramiro de Maeztu 9, E-28040 Madrid, Spain.
René UllrichInternational Institute Zittau (IHIZ), Technische Universität Dresden, Markt 23, D-02763 Zitau, Germany.ORCID 0000-0002-9165-6341
Martin HofrichterInternational Institute Zittau (IHIZ), Technische Universität Dresden, Markt 23, D-02763 Zitau, Germany.
Angel T MartínezCentro de Investigaciones Biológicas "Margarita Salas" (CIB), Consejo Superior de Investigaciones Científicas (CSIC), Ramiro de Maeztu 9, E-28040 Madrid, Spain.ORCID 0000-0002-1584-2863
Ana GutiérrezInstituto de Recursos Naturales y Agrobiología de Sevilla (IRNAS), Consejo Superior de Investigaciones Científicas (CSIC), Reina Mercedes 10, E-41012 Seville, Spain.
Consejo Superior de Investigaciones Científicas · ESInternational University Institute · DE

Funding

European Commission H2020-BBI-JU grant number 792063
6 · The paper itself

Abstract

Epoxide metabolites from n-3 and n-6 polyunsaturated fatty acids arouse interest thanks to their physiological and pharmacological activities. Their chemical synthesis has significant drawbacks, and enzymes emerge as an alternative with potentially higher selectivity and greener nature. Conversion of eleven eicosanoid, docosanoid, and other n-3/n-6 fatty acids into mono-epoxides by fungal unspecific peroxygenases (UPOs) is investigated, with emphasis on the

Indexed as

bioactive compoundschiral HPLCepoxylipidsNMRomega 3 (n-3) fatty acidsomega 6 (n-6) fatty acidspolyunsaturated fatty acidsregioselective synthesisstereoselective synthesisunspecific peroxygenases

Identifiers

PMID34942990
PMCPMC8698580
OpenAlexW3216784029

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.