Evidence map›Paper›PMID 34942962›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Bioactive Compounds in Oxidative Stress-Mediated Diseases: Targeting the NRF2/ARE Signaling Pathway and Epigenetic Regulation.

Muthu Thiruvengadam, Baskar Venkidasamy, Umadevi Subramanian, Ramkumar Samynathan, Mohammad Ali Shariati, Maksim Rebezov, Shabari Girish, Sivakumar Thangavel, Anand Raj Dhanapal, Natalya Fedoseeva and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed, 3 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

135 citing papers in PubMed, 3 syntheses or guidelines pooled it, 234 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  19. High-intensity interval training andResearch in pharmaceutical sciences · 2026
    Article
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75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Muthu ThiruvengadamDepartment of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul 05029, Korea.ORCID 0000-0003-0986-5484
Baskar VenkidasamyDepartment of Biotechnology, Sri Shakthi Institute of Engineering and Technology, Coimbatore 641062, Tamil Nadu, India.
Umadevi SubramanianTranslational Research Platform for Veterinary Biologicals, Tamil Nadu Veterinary and Animal Sciences University, Madhavaram Milk Colony, Chennai 600051, Tamil Nadu, India.
Ramkumar SamynathanR&D Division Alchem Diagnostics, New No. 1/1, Old No. 78, Gokhale Street, Ramnagar, Coimbatore 641009, Tamil Nadu, India.
Mohammad Ali ShariatiResearch Department, K.G. Razumovsky Moscow State University of Technologies and Management, 73 Zemlyanoy Val, 109004 Moscow, Russia.ORCID 0000-0001-9376-5771
Maksim RebezovSchool of Agricultural Sciences, Liaocheng University, 34 Wenhua Road, Liaocheng 252000, China.ORCID 0000-0003-0857-5143
Shabari GirishSchool of Life Sciences, St. Joseph College (Autonomous), Bengaluru 560027, Karnataka, India.ORCID 0000-0002-6525-8921
Sivakumar ThangavelPost Graduate Department of Microbiology, Ayya Nadar Janaki Ammal College, Sivakasi 626124, Tamil Nadu, India.
Anand Raj DhanapalDepartment of Biotechnology, Karpagam Academy of Higher Education, Coimbatore 641021, Tamil Nadu, India.
Natalya FedoseevaDepartment of Zootechnii, Production and Processing of Livestock Products, Russian State Agrarian Correspondence University, 50 Shosse Entuziastov, 143907 Balashikha, Russia.
Joohyun LeeDepartment of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul 05029, Korea.
Ill-Min ChungDepartment of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul 05029, Korea.
Konkuk University · KRLiaocheng University · CNKarpagam Academy of Higher Education · INRussian State Agrarian Correspondence University · RUSt. Joseph Dental College · INTranslational Research Platform for Veterinary Biologicals (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is a pathological condition occurring due to an imbalance between the oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 (NRF2), encoded by the gene

Indexed as

cancerdiabetesepigenetic modificationNRF2oxidative stressphytochemicals

Identifiers

PMID34942962
PMCPMC8698417
OpenAlexW3216764861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.