Evidence map›Paper›PMID 34942929›Full record

ArticleBrain sciences2021

A Mechanism-Based Approach to Anti-Aggression Psychotherapy in Borderline Personality Disorder: Group Treatment Affects Amygdala Activation and Connectivity.

Corinne Neukel, Katja Bertsch, Marc Wenigmann, Karen Spieß, Marlene Krauch, Sylvia Steinmann, Sabine C Herpertz

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Psychosocial functioning in personality disorders.Borderline personality disorder and emotion dysregulation · 2025
    Review
  4. Review
  5. Article
  6. Borderline Personality Disorder: Updates in a Postpandemic World.Focus (American Psychiatric Publishing) · 2022
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Corinne NeukelDepartment of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty, Heidelberg University, 69115 Heidelberg, Germany.
Katja BertschDepartment of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty, Heidelberg University, 69115 Heidelberg, Germany.
Marc WenigmannDepartment of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty, Heidelberg University, 69115 Heidelberg, Germany.
Karen SpießDepartment of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty, Heidelberg University, 69115 Heidelberg, Germany.
Marlene KrauchDepartment of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty, Heidelberg University, 69115 Heidelberg, Germany.
Sylvia SteinmannDepartment of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany.
Sabine C HerpertzDepartment of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty, Heidelberg University, 69115 Heidelberg, Germany.

Funding

Federal Ministry of Education and Research HE 2660/12-2
6 · The paper itself

Abstract

Aggression is highly prevalent in borderline personality disorder (BPD). Previous studies have identified specific biobehavioral mechanisms underlying aggression in BPD, threat sensitivity being among them. We composited the mechanism-based anti-aggression psychotherapy (MAAP) in order to target these specific mechanisms, and MAAP was found to be superior to non-specific supportive psychotherapy (NSSP) in reducing aggressive behavior. In the present study, we investigated whether underlying brain mechanisms expected to be involved were affected by MAAP. To this end,

Indexed as

aggressive behaviorborderline personality disorderemotional face matchingmechanisms of reactive aggressionpsychotherapythreat sensitivity

Identifiers

PMID34942929
PMCPMC8699721

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.