ReviewBrain sciences2021
Semantic Variant Primary Progressive Aphasia: Practical Recommendations for Treatment from 20 Years of Behavioural Research.
Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An international core outcome set for primary progressive aphasia (COS-PPA): Consensus-based recommendations for communication interventions across research and clinical settings.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- Augmenting Verb-Naming Therapy With Neuromodulation Decelerates Language Loss in Primary Progressive Aphasia.American journal of speech-language pathology · 2025Trial
- Comparing the value of dynamic versus static image-based tests of emotion recognition in neurodegenerative disease.Journal of neuropsychology · 2026Article
- Disentangling phonology from phonological short-term memory in Alzheimer's disease phenotypes.Alzheimer's research & therapy · 2025Article
- Feasibility of Home-Based Transcranial Direct Current Stimulation with Telerehabilitation in Primary Progressive Aphasia-A Case Series.Brain sciences · 2025Article
- Data-driven classification of narrative speech characteristics in stroke aphasia distinguishes neurological and strategic contributions.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- A spouse's perspective on communication breakdowns and supportive strategies for semantic variant primary progressive aphasia.Aphasiology · 2025Article
- The Quebec Semantic Memory Battery: Development, Standardization, and Psychometric Assessment of a Semantic Memory Battery in French.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Protocol for a multisite study on the efficacy of transcranial direct current stimulation as an adjuvant to naming and spelling therapy in the treatment of oral and written naming in individuals with primary progressive aphasia.Frontiers in human neuroscience · 2025Article
- Clinical Manifestations and Neural Basis of Semantic Dementia: Converging Evidences From Brain Imaging Studies.Clinical interventions in aging · 2025Review
- Advancing Neuropsychological Rehabilitation in Primary Progressive Aphasia Based on Principles of Cognitive Neuroscience: A Scoping Review and Systematic Analysis of the Data.Brain sciences · 2024Article
- Rehabilitation Services for Young-Onset Dementia: Examples from High- and Low-Middle-Income Countries.International journal of environmental research and public health · 2024Review
- Article
- Gesture profiles distinguish primary progressive aphasia variants: A preliminary study.Aphasiology · 2024Article
- Gesture profiles distinguish primary progressive aphasia variants.bioRxiv : the preprint server for biology · 2023Article
- Silent Pauses and Speech Indices as Biomarkers for Primary Progressive Aphasia.Medicina (Kaunas, Lithuania) · 2022Article
- Advances in Primary Progressive Aphasia.Brain sciences · 2022Article
- Access, referral, service provision and management of individuals with primary progressive aphasia: A survey of speech-language therapists in Italy.International journal of language & communication disordersArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
People with semantic variant primary progressive aphasia (svPPA) present with a characteristic progressive breakdown of semantic knowledge. There are currently no pharmacological interventions to cure or slow svPPA, but promising behavioural approaches are increasingly reported. This article offers an overview of the last two decades of research into interventions to support language in people with svPPA including recommendations for clinical practice and future research based on the best available evidence. We offer a lay summary in English, Spanish and French for education and dissemination purposes. This paper discusses the implications of right- versus left-predominant atrophy in svPPA, which naming therapies offer the best outcomes and how to capitalise on preserved long-term memory systems. Current knowledge regarding the maintenance and generalisation of language therapy gains is described in detail along with the development of compensatory approaches and educational and support group programmes. It is concluded that there is evidence to support an integrative framework of treatment and care as best practice for svPPA. Such an approach should combine rehabilitation interventions addressing the language impairment, compensatory approaches to support activities of daily living and provision of education and support within the context of dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.