Evidence map›Paper›PMID 34942643›Full record

ReviewJournal of cognitive neuroscience2022

Novel Cognitive Functions Arise at the Convergence of Macroscale Gradients.

Heejung Jung, Tor D Wager, R McKell Carter

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Resolving the Abstract-Concrete Paradox in the Angular Gyrus: A Multimethod Investigation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  2. What episodic memory reveals about the default mode network.Current opinion in behavioral sciences · 2026
    Article
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  12. Neural Support for Contributions of Utility and Narrative Processing of Evidence in Juror Decision Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Heejung JungUniversity of Colorado, Boulder.ORCID 0000-0001-5839-1655
Tor D WagerUniversity of Colorado, Boulder.
R McKell CarterUniversity of Colorado, Boulder.ORCID 0000-0003-2235-6529
Dartmouth College · USUniversity of Colorado Boulder · US

Funding

Dynamic brain representations underlying emotional experienceR01MH116026 · NIMH · DARTMOUTH COLLEGE · PI CHANG, LUKE JOSEPH · 2018 to 2025
$4.9M
Individualized spatial topology in functional neuroimagingR01EB026549 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Abhirup Datta, Martin Lindquist · 2018 to 2026
$4.5M
NIBIB NIH HHS EB026549-01NIBIB NIH HHS R01 EB026549NIMH NIH HHS MH116026NIMH NIH HHS R01 MH116026
6 · The paper itself

Abstract

Functions in higher-order brain regions are the source of extensive debate. Past trends have been to describe the brain in terms of a set of functional modules, especially posterior cortical areas, but a new emerging paradigm focuses on interactions between neighboring representations. In this review, we synthesize emerging evidence that a variety of novel functions in the higher-order brain regions are due to convergence. Convergence of macroscale gradients brings feature-rich representations into close proximity, presenting an opportunity for novel functions to arise. Using the TPJ as an example, we demonstrate that convergent areas have three properties, they: (1) are at the peak of the processing hierarchy, (2) combine the most abstracted representations, and (3) are equidistant from other convergent areas. As information moves from primary sensory cortices to higher-order brain regions, it becomes abstracted and hierarchical. Eventually, these processing gradients converge at a point equally and maximally distant from their sensory origins. This convergence, which produces multifaceted cognitive functions, such as mentalizing another person's thoughts or projecting into a future space, parallels evolutionary and developmental characteristics of such regions, resulting in new cognitive and affective faculties.

Indexed as

Brain MappingCognitionBrainHumans

Identifiers

PMID34942643
PMCPMC9365194
OpenAlexW4200204431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.