ArticleNature2022
Evolution of enhanced innate immune evasion by SARS-CoV-2.
Erratum issuedOpen access · hybridAbstract read
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 254 papers.
0numbers the graph read from it
0cells of the map it votes in
254citing papers in PubMed
21.7field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
254 citing papers in PubMed, 395 citations in OpenAlex.
- Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- APOBEC3-driven attenuation of the 2022 global outbreak monkeypox virus relative to its clade IIb ancestor.Nature communications · 2026Article
- Molecular mechanism by which SARS-CoV-2 Orf9b suppresses the Tom70-Hsp90 interaction to evade innate immunity.Science advances · 2026Article
- RAPID: evaluation of Cas12a protospacer nicking and chimeric reporters for PAM-independent RNA and DNA diagnostics.Nucleic acids research · 2026Article
- DNA oligonucleotides block viral entry of SARS-CoV-2 Omicron variants.PLoS pathogens · 2026Article
- Age-dependent expression and antiviral activity of interferon epsilon in respiratory epithelium.Journal of virology · 2026Article
- Global disparities in COVID-19 vaccine coverage associated with trajectories of SARS-CoV-2 adaptation.BMC infectious diseases · 2026Article
- Exploring Key Regulators of Mitochondrial Dynamics and Immune Response in SARS-CoV-2 Infection.Viruses · 2026Article
- Coronavirus protein interaction mapping in bat and human cells reveals network rewiring governing immune evasion and zoonotic potential.Cell host & microbe · 2026Article
- Targeting SARS-CoV-2 Structural and Accessory Proteins: Emerging Opportunities for Small-Molecule Coronavirus Antivirals.Pharmaceutics · 2026Review
- SARS-CoV-2 Nsp1 suppresses the canonical NF-κB pathway by promoting ubiquitin-dependent degradation of TAK1 kinase.PLoS pathogens · 2026Article
- Inhibiting the interaction between the mitochondrial receptor Tom70 and SARS CoV 2 Orf9b with small molecules.bioRxiv : the preprint server for biology · 2026Article
- RNA-binding proteins: a comprehensive review of multifaceted regulatory mechanisms in neuroinflammation and implications in the pathogenesis of neurological disorders.Journal of neuroinflammation · 2026Review
- An emerging human eye disease is associated with aquatic virus zoonotic infection.Nature microbiology · 2026Article
- Evolution of a truncated nucleocapsid protein enhances SARS-CoV-2 fitness by suppressing antiviral responses.PLoS biology · 2026Article
- Viral evolution during primary infection in immunocompromised hosts.PLoS computational biology · 2026Article
- Stealth replication of SARS-CoV-2 Omicron in the nasal epithelium at physiological temperature.Journal of virology · 2026Article
- SARS-CoV-2 peptide fragments selectively dysregulate specific immune cell populations via Gaussian curvature targeting.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- SARS-CoV-2 intra-host evolution during acute infection in COVID-19 patients.Frontiers in microbiology · 2026Article
- How benchmarking of bioinformatics tools is essential for informed workflow selection: a case study on SARS-CoV-2 subgenomic RNA detection.Frontiers in bioinformatics · 2026Article
194 more citing papers are in PubMed but not listed here.
Corrections and comments
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- Erratum issued
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Authors and funding
43 authors at 10 institutions in 2 countries.
Lucy G Thorne *Division of Infection and Immunity, University College London, London, UK.ORCID http://orcid.org/0000-0001-7358-6047
Mehdi Bouhaddou *QBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Ann-Kathrin Reuschl *Division of Infection and Immunity, University College London, London, UK.
Lorena Zuliani-Alvarez *QBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Ben PolaccoQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-1570-9234
Adrian PelinQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Jyoti BatraQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Matthew V X WhelanDivision of Infection and Immunity, University College London, London, UK.
Myra HosmilloDivision of Virology, Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
Andrea FossatiQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-5170-4903
Roberta RagazziniEpithelial Stem Cell Biology and Regenerative Medicine Laboratory, The Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0003-2186-293X
Irwin JungreisMIT Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-3197-5367
Manisha UmmadiQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Ajda RojcQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Jane TurnerDivision of Infection and Immunity, University College London, London, UK.
Marie L BischofDivision of Infection and Immunity, University College London, London, UK.
Kirsten ObernierQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-4025-1299
Hannes BrabergQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-7070-2257
Margaret SoucherayQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Alicia RichardsQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Kuei-Ho ChenQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-6541-0578
Bhavya HarjaiQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Danish MemonEuropean Molecular Biology Laboratory (EMBL), European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, UK.ORCID http://orcid.org/0000-0002-1365-0710
Joseph HiattQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Romel RosalesDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Briana L McGovernDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-0492-9904
Aminu JahunDivision of Virology, Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-4585-1701
Jacqueline M FabiusQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Kris WhiteDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-0889-0506
Ian G GoodfellowDivision of Virology, Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-9483-510X
Yasu TakeuchiDivision of Infection and Immunity, University College London, London, UK.
Paola BonfantiEpithelial Stem Cell Biology and Regenerative Medicine Laboratory, The Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0001-9655-3766
Kevan ShokatQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-8590-7741
Natalia JuraQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-5129-641X
Klim VerbaQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-2238-8590
Mahdad NoursadeghiDivision of Infection and Immunity, University College London, London, UK.ORCID http://orcid.org/0000-0002-4774-0853
Pedro BeltraoQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.
Manolis KellisMIT Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-7113-9630
Danielle L SwaneyQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-6119-6084
Adolfo García-SastreDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-6551-1827
Clare JollyDivision of Infection and Immunity, University College London, London, UK. c.jolly@ucl.ac.uk.ORCID http://orcid.org/0000-0002-4603-2281
Greg J TowersDivision of Infection and Immunity, University College London, London, UK. g.towers@ucl.ac.uk.ORCID http://orcid.org/0000-0002-7707-0264
Nevan J KroganQBI Coronavirus Research Group (QCRG), University of California San Francisco, San Francisco, CA, USA. nevan.krogan@ucsf.edu.ORCID http://orcid.org/0000-0003-4902-337X
Gladstone Institutes · USUniversity College London · GBIcahn School of Medicine at Mount Sinai · USUniversity of Cambridge · GBBroad Institute · USEuropean Bioinformatics Institute · GBThe Francis Crick Institute · GBUniversity of California, San Francisco · USQB3 · USThe London College · GB
Funding
NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00014 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GARCIA-SASTRE, ADOLFO · 2021 to 2025
$62.6MThe role of Listeria cyclic-di-AMP during infection and immunityP01AI063302 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI PORTNOY, DANIEL A · 2004 to 2025
$45.5MSARS-CoV adaptations through a Systems Biology Lens (SYBIL)U19AI135972 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Adolfo Garcia-Sastre · 2018 to 2026
$27.2MRESEARCH PROJECT 2U19AI135990 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nevan J Krogan · 2018 to 2026
$21.4MX-ray Screening and Rapid Structure DeterminationP50AI150476 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KROGAN, NEVAN J · 2019 to 2021
$14.4MMedical Scientist Training Program (T32 NRSA Training Grant)T32GM141323 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Aimee Kao · 2021 to 2026
$10.5MVulnerability of SARS- CoV-2 Infection in Lung Cancer Based on Serological Antibody AnalysesU54CA260560 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SHYR, YU · 2020 to 2024
$10.0MNovel VP30-host Interactions that Negatively Regulate Ebola Virus InfectionR01AI143292 · NIAID · WASHINGTON UNIVERSITY · PI AMARASINGHE, GAYA K., BASLER, CHRISTOPHER F · 2019 to 2023
$4.0MDiscovery of novel, ubiquitin-regulated mechanisms of TB control by macrophagesR01AI120694 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COX, JEFFERY S, KROGAN, NEVAN J · 2015 to 2019
$3.3MA universal multiplexing approach to unlock the hidden proteomeR01GM133981 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SWANEY, DANIELLE L · 2019 to 2022
$1.3MSystematic Targeting of Oncogene Interacting Proteins to Reveal New Therapeutic StrategiesF32CA239333 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BOUHADDOU, MEHDI · 2019 to 2021
$192kMedical Research Council G0801172Medical Research Council MR/S023380/1Medical Research Council MR/W005611/1NCI NIH HHS F32 CA239333NCI NIH HHS U54 CA260560NIAID NIH HHS 75N93021C00014NIAID NIH HHS HHSN272201400008CNIAID NIH HHS P01 AI063302NIAID NIH HHS P50 AI150476NIAID NIH HHS R01 AI120694NIAID NIH HHS R01 AI143292NIAID NIH HHS U19 AI135972NIAID NIH HHS U19 AI135990NIGMS NIH HHS R01 GM133981NIGMS NIH HHS T32 GM141323Wellcome Trust 108079Wellcome Trust 206298Wellcome Trust 207498Wellcome Trust 207498/Z/17/ZWellcome Trust 207511Wellcome Trust 207511/Z/17/ZWellcome Trust 223065
Abstract
The emergence of SARS-CoV-2 variants of concern suggests viral adaptation to enhance human-to-human transmission
Indexed as
Evolution, MolecularImmune EvasionCoronavirus Nucleocapsid ProteinsCOVID-19HumansImmunity, InnateInterferonsMitochondrial Precursor Protein Import Complex ProteinsPhosphoproteinsPhosphorylationProteomicsRNA-SeqRNA, ViralSARS-CoV-2Coronavirus Nucleocapsid ProteinsInterferonsMitochondrial Precursor Protein Import Complex Proteinsnucleocapsid phosphoprotein, SARS-CoV-2PhosphoproteinsRNA, ViralTOMM70 protein, human
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.