ArticleNature2022
Broadly neutralizing antibodies target a haemagglutinin anchor epitope.
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Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers.
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134citing papers in PubMed
16.9field-weighted citation impact, top 1% of its field
What it found
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Who cites it
134 citing papers in PubMed, 181 citations in OpenAlex.
- Nanoemulsion adjuvanted COBRA HA vaccine enhances protective antibody titers against H1N1 and H3N2 influenza viruses.Human vaccines & immunotherapeutics · 2026Article
- Some Exposure for Influenza Hemagglutinin Interface Antibodies.Immunological reviews · 2026Review
- What Antibody Repertoires See: Structural and Immunogenetic Insights Into Influenza A Virus Hemagglutinin Recognition.Immunological reviews · 2026Review
- Advances in the Development of a Universal Influenza Vaccine.Antibodies (Basel, Switzerland) · 2026Review
- Pre-existing hemagglutinin-specific antibody levels are associated with B-cell repertoire maturation and antibody breadth after influenza vaccination.Virologica Sinica · 2026Article
- The Influenza-Specific Immunoglobulin Repertoire - Nimble Yet Steeped in Tradition.Immunological reviews · 2026Review
- Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies.Immunological reviews · 2026Review
- Optimizing an avian influenza vaccine using a novel Bacterial Enzymatic Combinatorial Chemistry (BECC) TLR4 adjuvant.mSphere · 2026Article
- H3BERTa: A CDR-H3-specific language model for antibody repertoire analysis.Patterns (New York, N.Y.) · 2026Article
- Stabilized mosaic hemagglutinin immunogens as novel universal influenza virus vaccines.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Structural basis for distinct protective mechanisms of IGHV3-23 antibodies targeting influenza hemagglutinin stem.Nature communications · 2026Article
- Egyptian rousette bat humoral immunity to H9 influenza hemagglutinin.bioRxiv : the preprint server for biology · 2026Article
- A C-type single-domain antibody with protective efficacy against H1N1 via respiratory administration.Virologica Sinica · 2026Article
- A dual-adjuvanted HA stem nanoparticle vaccine elicits a multifunctional antibody response that is associated with protection in newborn monkeys.Cell reports. Medicine · 2026Article
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- DM: a simple solution to suppress air-water interface interactions in cryo-EM.bioRxiv : the preprint server for biology · 2026Article
- Scalable secretory production of influenza A (H1N1) hemagglutinin HA1 in Pichia pastoris through expression and process optimization.Microbial cell factories · 2026Article
- DNA Nanostructure-Templated Multivalency Enables Broad-Spectrum Virus Inhibition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
74 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors at 10 institutions in 2 countries.
Jenna J Guthmiller *Department of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA. jguthmiller@uchicago.edu.ORCID http://orcid.org/0000-0001-7566-3536
Julianna Han *Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-3402-2609
Henry A UtsetDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.
Lei LiDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.
Linda Yu-Ling LanCommittee on Immunology, University of Chicago, Chicago, IL, USA.
Carole HenryDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.
Christopher T StamperCommittee on Immunology, University of Chicago, Chicago, IL, USA.
Meagan McMahonDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
George O'DellDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Monica L Fernández-QuinteroCenter for Molecular Biosciences Innsbruck, Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria.
Alec W FreynDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Fatima AmanatDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-8029-8227
Olivia StovicekDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-6413-855X
Lauren GentlesBasic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Sara T RicheyDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Alba Torrents de la PeñaDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
Victoria RosadoDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Haley L DuganCommittee on Immunology, University of Chicago, Chicago, IL, USA.
Nai-Ying ZhengDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.
Micah E TeporaDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.
Dalia J BitarDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.
Siriruk ChangrobDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-1826-4333
Shirin StrohmeierDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Min HuangDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA.
Adolfo García-SastreDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-6551-1827
Klaus R LiedlCenter for Molecular Biosciences Innsbruck, Department of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-0985-2299
Jesse D BloomBasic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-1267-3408
Raffael NachbagauerDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-5568-5420
Peter PaleseDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-0337-5823
Florian KrammerDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-4121-776X
Lynda CoughlanDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-9880-6560
Andrew B WardDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA. andrew@scripps.edu.ORCID http://orcid.org/0000-0001-7153-3769
Patrick C WilsonDepartment of Medicine, Section of Rheumatology, University of Chicago, Chicago, IL, USA. pcw4001@med.cornell.edu.
University of Chicago · USIcahn School of Medicine at Mount Sinai · USScripps Research Institute · USModerna Therapeutics (United States) · USUniversität Innsbruck · ATCornell University · USHoward Hughes Medical Institute · USTisch Hospital · USUniversity of Maryland, Baltimore · USUniversity of Washington · US
Funding
COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTER: UNIVERSAL INFLUENZA VACCINE RESEARCH75N93019C00051 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2019 to 2025
$105.4MVACCINE INDUCED IMMUNITY IN THE YOUNG AND AGEDU19AI057266 · NIAID · EMORY UNIVERSITY · PI Rafi Ahmed · 2003 to 2026
$81.7MToward a Universal Influenza Virus VaccineP01AI097092 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PALESE, PETER · 2012 to 2022
$17.6MUnderstanding Human B Cell Responses to Influenza to Improve the Influenza U19AI109946 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RAVETCH, JEFFREY VICTOR · 2014 to 2018
$9.6MPATHOGENESIS AND IMMUNOLOGY OF DISEASET32AI007244 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI NEMAZEE, DAVID · 1985 to 2022
$8.8MEvaluation of the FcgR mechanisms in the antibody-dependent enhancement of SARS-CoV-2 infectionR01AI145870 · NIAID · ROCKEFELLER UNIVERSITY · PI Peter Palese, JEFFREY Victor RAVETCH · 2019 to 2026
$8.4MUniversity of Chicago Autoimmunity Center of ExcellenceU19AI082724 · NIAID · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 2009 to 2023
$7.2MHigh-throughput experiments to guide influenza vaccine strain selectionR01AI127893 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BLOOM, JESSE D · 2016 to 2020
$2.1MGeneration of a polycistronic universal influenza virus vaccine based on rare species adenoviral vectorsR21AI146529 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI COUGHLAN, LYNDA · 2019 to 2020
$466kExosome-display as a strategy to enhance the immunogenicity of SARS-CoV-2 vaccines based on adenoviral vectorsR21AI157606 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI COUGHLAN, LYNDA · 2020 to 2020
$425kInvestigating the development and clonal dynamics of broadly neutralizing B cells against influenza virusesK99AI159136 · NIAID · UNIVERSITY OF CHICAGO · PI GUTHMILLER, JENNA · 2021 to 2021
$104kNIAID NIH HHS 75N93019C00051NIAID NIH HHS K99 AI159136NIAID NIH HHS P01 AI097092NIAID NIH HHS R01 AI127893NIAID NIH HHS R01 AI145870NIAID NIH HHS R21 AI146529NIAID NIH HHS R21 AI157606NIAID NIH HHS T32 AI007244NIAID NIH HHS U19 AI057266NIAID NIH HHS U19 AI082724NIAID NIH HHS U19 AI109946
Abstract
Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential to provide near universal protection against influenza virus infection
Indexed as
Antibodies, NeutralizingAntibodies, ViralBroadly Neutralizing AntibodiesEpitopesHemagglutinin Glycoproteins, Influenza VirusHumansInfluenza, HumanInfluenza VaccinesMemory B CellsAntibodies, NeutralizingAntibodies, ViralBroadly Neutralizing AntibodiesEpitopesHemagglutinin Glycoproteins, Influenza VirusInfluenza Vaccines
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