Evidence map›Paper›PMID 34941968›Full record

ArticlePloS one2021

Seroprevalence of antibodies against SARS-Cov-2 in the high impacted sub-district in Jakarta, Indonesia.

Olivia Herlinda, Adrianna Bella, Gita Kusnadi, Dimitri Swasthika Nurshadrina, Mochamad Thoriq Akbar, Sofwatun Nida, Ngabila Salama, Iwan Ariawan, Diah Saminarsih

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dynamics of SARS-CoV-2 seroassay sensitivity: a systematic review and modelling study.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olivia HerlindaCenter for Indonesia's Strategic Development Initiatives (CISDI), Jakarta, Indonesia.
Adrianna BellaCenter for Indonesia's Strategic Development Initiatives (CISDI), Jakarta, Indonesia.ORCID 0000-0002-2731-2704
Gita KusnadiCenter for Indonesia's Strategic Development Initiatives (CISDI), Jakarta, Indonesia.
Dimitri Swasthika NurshadrinaCenter for Indonesia's Strategic Development Initiatives (CISDI), Jakarta, Indonesia.
Mochamad Thoriq AkbarCenter for Indonesia's Strategic Development Initiatives (CISDI), Jakarta, Indonesia.ORCID 0000-0003-4984-7360
Sofwatun NidaCenter for Indonesia's Strategic Development Initiatives (CISDI), Jakarta, Indonesia.
Ngabila SalamaJakarta Provincial Health Office, Jakarta, Indonesia.
Iwan AriawanFaculty of Public Health, Universitas Indonesia, Depok, Indonesia.
Diah SaminarsihWorld Health Organization, Geneva, Switzerland.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundUnderstanding the actual prevalence of COVID-19 transmission in the community is vital for strategic responses to the pandemic. This study aims to estimate the actual infection of COVID-19 through a seroprevalence survey and to predict infection fatality rate (IFR) in Tanjung Priok, the hardest-hit sub-district by the COVID-19 in Jakarta, Indonesia.

methodsWe conducted a venous blood sampling (phlebotomy) to 3,196 individuals in Tanjung Priok between Nov 23, 2020, and Feb 19, 2021 to detect their antibodies against SARS-CoV-2. Using an enumerator-administered questionnaire, we collected data on the respondents' demographic characteristics, COVID-19 test history, COVID-19 symptoms in the last 14 days, comorbidities, and protective behaviours during the last month. We employed descriptive analysis to estimate the seroprevalence and IFR.

findingsThe prevalence of Antibody against SARS-CoV-2 was 28.52% (95% CI 25.44-31.81%), with the result being higher in females than males (OR 1.20; 95% CI 1.02-1.42). By the end of the data collection (February 9, 2021), the cumulative cases of COVID-19 in Tanjung Priok were reported to be experienced by 9,861 people (2.4%). Those aged 45-65 were more likely to be seropositive than 15-19 years old (OR 1.42; 95% CI 1.05-1.92). Nearly one third (31%) of the subjects who developed at least one COVID-19 symptom in the last 14 days of the data collection were seropositive. The estimated IFR was 0.08% (95% CI 0.07-0.09), with a higher figure recorded in males (0.09; 95% CI 0.08-0.10) than females (0.07; 95% CI 0.06-0.08), and oldest age group (45-65) (0.21; 95% CI 0.18-0.23) than other younger groups.

conclusionAn under-reporting issue was found between the estimated COVID-19 seroprevalence and the reported cumulative cases in Tanjung Priok. More efforts are required to amplify epidemiological surveillance by the provincial and local governments.

Indexed as

Seroepidemiologic StudiesAdolescentAdultAgedAged, 80 and overAntibodies, ViralChildCOVID-19Diagnostic Tests, RoutineFemaleHumansIndonesiaMaleMiddle AgedPandemicsSARS-CoV-2Antibodies, Viral

Identifiers

PMID34941968
PMCPMC8699601

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.