Evidence map›Paper›PMID 34941955›Full record

ArticlePloS one2021

Diagnostic and prognostic significance of premature ventricular complexes in community and hospital-based participants: A scoping review.

Sukardi Suba, Kirsten E Fleischmann, Hildy Schell-Chaple, Priya Prasad, Gregory M Marcus, Xiao Hu, Michele M Pelter

Open access · goldAbstract readScoping Review
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Sukardi SubaSchool of Nursing, University of Rochester Medical Center, Rochester, New York, United States of America.ORCID 0000-0002-0756-5720
Kirsten E FleischmannDepartment of Medicine, Division of Cardiology, School of Medicine, University of California, San Francisco, San Francisco, California, United States of America.
Hildy Schell-ChapleInstitute for Nursing Excellence, University of California, San Francisco, Medical Center, San Francisco, California, United States of America.
Priya PrasadDepartment of Medicine, Division of Hospital Medicine, School of Medicine, University of California, San Francisco, San Francisco, California, United States of America.
Gregory M MarcusDepartment of Medicine, Division of Cardiology, School of Medicine, University of California, San Francisco, San Francisco, California, United States of America.
Xiao HuSchool of Nursing, Duke University, Durham, North Carolina, United States of America.
Michele M PelterDepartment of Physiological Nursing, University of California, San Francisco, California, United States of America.ORCID 0000-0001-9456-228X
University of California, San Francisco · USDuke University · USUniversity of California San Francisco Medical Center · USUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile there are published studies that have examined premature ventricular complexes (PVCs) among patients with and without cardiac disease, there has not been a comprehensive review of the literature examining the diagnostic and prognostic significance of PVCs. This could help guide both community and hospital-based research and clinical practice.

methodsScoping review frameworks by Arksey and O'Malley and the Joanna Briggs Institute (JBI) were used. A systematic search of the literature using four databases (CINAHL, Embase, PubMed, and Web of Science) was conducted. The review was prepared adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Review (PRISMA-ScR).

resultsA total of 71 relevant articles were identified, 66 (93%) were observational, and five (7%) were secondary analyses from randomized clinical trials. Three studies (4%) examined the diagnostic importance of PVC origin (left/right ventricle) and QRS morphology in the diagnosis of acute myocardial ischemia (MI). The majority of the studies examined prognostic outcomes including left ventricular dysfunction, heart failure, arrhythmias, ischemic heart diseases, and mortality by PVCs frequency, burden, and QRS morphology.

conclusionsVery few studies have evaluated the diagnostic significance of PVCs and all are decades old. No hospital setting only studies were identified. Community-based longitudinal studies, which make up most of the literature, show that PVCs are associated with structural and coronary heart disease, lethal arrhythmias, atrial fibrillation, stroke, all-cause and cardiac mortality. However, a causal association between PVCs and these outcomes cannot be established due to the purely observational study designs employed.

Indexed as

Atrial FibrillationCoronary DiseaseStrokeVentricular Premature ComplexesDisease-Free SurvivalHumansSurvival Rate

Identifiers

PMID34941955
PMCPMC8699640
OpenAlexW4200120906

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.