Evidence map›Paper›PMID 34941824›Full record

ArticleVeterinary sciences2021

Milk Somatic Cell Count and Polymorphonuclear Cells in Healthy Quarters of Cows That Underwent Blanket and Selective Dry Therapy: An Italian Case Study.

Angela Costa, Massimo De Marchi, Daniele Sagrafoli, Hillary Lanzi, Simonetta Amatiste, Carlo Boselli, Giuseppina Giacinti

Abstract read
In one paragraph

Article in Veterinary sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angela CostaDepartment of Agronomy, Food, Natural Resources, Animals and Environment (DAFNAE), University of Padova, Viale dell'Università 16, 35020 Legnaro, Italy.ORCID 0000-0001-5353-8988
Massimo De MarchiDepartment of Agronomy, Food, Natural Resources, Animals and Environment (DAFNAE), University of Padova, Viale dell'Università 16, 35020 Legnaro, Italy.
Daniele SagrafoliExperimental Zooprophylactic Institute Lazio and Toscana Mariano Aleandri, Via Appia Nuova 1411, 00178 Rome, Italy.
Hillary LanziPrivate Practitioner, Via San Benedetto, 26, 03010 Torre Cajetani, Italy.
Simonetta AmatisteExperimental Zooprophylactic Institute Lazio and Toscana Mariano Aleandri, Via Appia Nuova 1411, 00178 Rome, Italy.
Carlo BoselliExperimental Zooprophylactic Institute Lazio and Toscana Mariano Aleandri, Via Appia Nuova 1411, 00178 Rome, Italy.ORCID 0000-0002-3990-1063
Giuseppina GiacintiExperimental Zooprophylactic Institute Lazio and Toscana Mariano Aleandri, Via Appia Nuova 1411, 00178 Rome, Italy.ORCID 0000-0002-1496-3022

Funding

Ministero della Salute IZSLT 12/16 ("Studio di differenti protocolli per il trattamento selettivo della bovina da latte alla messa in asciutta")
6 · The paper itself

Abstract

The incidence of mastitis increases with parity in dairy cattle and multiparous cows are often treated at drying off to limit the risk of udder health issues and support mammary gland tissues recovery. Milk somatic cells count (SCC, cells/mL) comprises different white blood cells fractions and is worldwide used to monitor and genetically improve udder health. Nevertheless, only certain SCC fractions increase when an udder inflammation occurs. Considering that antibiotic use for preventive purposes will be forbidden in 2022, we compared two different dry therapy protocols, blanket (BDCT) and selective (SDCT), on different SCC fractions in healthy quarters milk. Multiparous Holstein cows were enrolled in a randomized controlled trial and SCC, neutrophils, macrophages, lymphocytes, polymorphonuclear cells (PMN) and differential somatic cell count (DSCC) recorded after the experimental drying off were available. Significant differences were observed between the two protocols, with more favorable parameters in BDCT than SDCT cows. Results showed that moving from BDCT to SDCT is expected to significantly increase some SCC fractions, such as PMN, in healthy quarters. The baseline SCC level at the onset of lactation was greater in cows under SDCT than BDCT. Although not significant, clinical mastitis prevalence was numerically lower in BDCT (7.32%) than SDCT (8.62%). In this study we referred to a limited number of cows, but still findings will be useful to improve the knowledge on the impact of SDCT on milk SCC fractions in healthy quarters.

Indexed as

differential somatic cellsdrying offmastitisneutrophilsudder health

Identifiers

PMID34941824
PMCPMC8705708

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.