Evidence map›Paper›PMID 34941771›Full record

ArticleToxics2021

Exposure to Sub-Lethal Doses of Permethrin Is Associated with Neurotoxicity: Changes in Bioenergetics, Redox Markers, Neuroinflammation and Morphology.

Teresita Guadalupe López-Aceves, Elvia Coballase-Urrutia, Francisco Estrada-Rojo, América Vanoye-Carlo, Liliana Carmona-Aparicio, María Eugenia Hernández, José Pedraza-Chaverri, Luz Navarro, Omar E Aparicio-Trejo, Armando Pérez-Torres and 8 more

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. AI/ML-based computational models for toxicity prediction.Environmental science and pollution research international · 2026
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Teresita Guadalupe López-AcevesRegional Graduate Program in Biotechnology, Faculty of Biological Chemical Sciences, Autonomous University of Sinaloa, Culiacán 80000, Mexico.
Elvia Coballase-UrrutiaLaboratory of Neuroscience, National Institute of Pediatrics, Mexico City 04530, Mexico.ORCID 0000-0002-1309-0784
Francisco Estrada-RojoDepartment of Physiology, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.ORCID 0000-0001-8964-6585
América Vanoye-CarloLaboratory of Neuroscience, National Institute of Pediatrics, Mexico City 04530, Mexico.ORCID 0000-0002-4539-4758
Liliana Carmona-AparicioLaboratory of Neuroscience, National Institute of Pediatrics, Mexico City 04530, Mexico.
María Eugenia HernándezSubdirection of Clinical Research, National Institute of Psychiatry, Mexico City 14370, Mexico.ORCID 0000-0001-8327-5939
José Pedraza-ChaverriDepartment of Biology, Faculty of Chemistry, National Autonomous University of Mexico, Mexico City 04150, Mexico.ORCID 0000-0001-6628-4411
Luz NavarroDepartment of Physiology, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.ORCID 0000-0002-5519-0871
Omar E Aparicio-TrejoDepartment of Biology, Faculty of Chemistry, National Autonomous University of Mexico, Mexico City 04150, Mexico.ORCID 0000-0002-7701-4537
Armando Pérez-TorresDepartment of Cell and Tissue Biology, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.ORCID 0000-0003-2519-7922
Omar N Medina-CamposDepartment of Biology, Faculty of Chemistry, National Autonomous University of Mexico, Mexico City 04150, Mexico.ORCID 0000-0001-8264-0412
Daniel Martínez-FongDepartment of Physiology, Biophysics and Neurosciences, Center for Research and Advanced Studies, Mexico City 07360, Mexico.
Vicente Sánchez-ValleNeuroplasticity and Neurodegeneration Laboratory, Department of Pharmacology, Center for Research and Advanced Studies, Mexico City 07360, Mexico.ORCID 0000-0001-6373-9089
Noemi Cárdenas-RodríguezLaboratory of Neuroscience, National Institute of Pediatrics, Mexico City 04530, Mexico.ORCID 0000-0002-6580-3440
Leticia Granados-RojasLaboratory of Neuroscience, National Institute of Pediatrics, Mexico City 04530, Mexico.
Evelyn Pulido-CamarilloDepartment of Cell and Tissue Biology, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Verónica Rodríguez-MataDepartment of Cell and Tissue Biology, Faculty of Medicine, National Autonomous University of Mexico, Mexico City 04510, Mexico.
Claudia Del R León-SicairosRegional Graduate Program in Biotechnology, Faculty of Biological Chemical Sciences, Autonomous University of Sinaloa, Culiacán 80000, Mexico.
Universidad Nacional Autónoma de México · MXUniversidad Autónoma de Sinaloa · MX

Funding

Secretaria de Salud, Instituto Nacional de Pediatría Protocolo 060/2018, Programa E022
6 · The paper itself

Abstract

Permethrin (PERM) is a member of the class I family of synthetic pyrethroids. Human use has shown that it affects different systems, with wide health dysfunctions. Our aim was to determine bioenergetics, neuroinflammation and morphology changes, as redox markers after subacute exposure to PERM in rats. We used MDA determination, protein carbonyl assay, mitochondrial O

Indexed as

bioenergeticsneuroinflammationneurotoxicitypermethrin

Identifiers

PMID34941771
PMCPMC8704605
OpenAlexW4200117402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.