Evidence map›Paper›PMID 34941748›Full record

Trial reportToxins2021

Effectiveness and Safety of Intradetrusor OnabotulinumtoxinA Injection for Neurogenic Detrusor Overactivity and Overactive Bladder Patients in Taiwan-A Phase IV Prospective, Interventional, Multiple-Center Study (Restore Study).

Chung-Cheng Wang, Eric Chieh-Lung Chou, Yao-Chi Chuang, Chih-Chieh Lin, Yu-Chao Hsu, Chun-Hou Liao, Hann-Chorng Kuo

Open access · goldAbstract readClinical Trial, Phase IVMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Chung-Cheng WangDepartment of Urology, En Chu Kong Hospital, New Taipei City 237414, Taiwan.ORCID 0000-0003-2629-4011
Eric Chieh-Lung ChouDepartment of Urology, China Medical University Hospital, School of Medicine, China Medical University, Taichung 406040, Taiwan.
Yao-Chi ChuangDepartment of Urology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, Taiwan.ORCID 0000-0002-1468-3792
Chih-Chieh LinShu-Tien Urological Research Center, Department of Urology, Taipei Veterans General Hospital, School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Yu-Chao HsuDepartment of Urology, Linko Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyung 333323, Taiwan.ORCID 0000-0003-3733-8155
Chun-Hou LiaoDepartment of Urology, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, New Taipei City 242062, Taiwan.ORCID 0000-0001-9414-8660
Hann-Chorng KuoDepartment of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Buddhist Tzu Chi University, Hualiang 970374, Taiwan.ORCID 0000-0001-7165-4771
Chang Gung University · TWChina Medical University · TWChung Yuan Christian University · TWFu Jen Catholic University · TWKaohsiung Chang Gung Memorial Hospital · TWNational Yang Ming Chiao Tung University · TWTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a phase IV, pre/post multi-center study to evaluate the efficacy and safety of intradetrusor onabotulinumtoxinA injection in patients with neurogenic detrusor overactivity (NDO,

Indexed as

AdultAgedAged, 80 and overBotulinum Toxins, Type AFemaleHumansMaleMiddle AgedMuscle HypertoniaProspective StudiesTaiwanUrinary Bladder, OveractiveYoung AdultBotulinum Toxins, Type Aonabotulinum toxin Aneurogenic detrusor overactivityonabotulinum toxin Aoveractive bladder

Identifiers

PMID34941748
PMCPMC8707051
OpenAlexW4200063376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.