Evidence map›Paper›PMID 34941700›Full record

ArticleToxins2021

Sequence, Structure, and Binding Site Analysis of Kirkiin in Comparison with Ricin and Other Type 2 RIPs.

Stefania Maiello, Rosario Iglesias, Letizia Polito, Lucía Citores, Massimo Bortolotti, José M Ferreras, Andrea Bolognesi

Open access · goldAbstract readComparative Study
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Stefania MaielloDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum-University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy.ORCID 0000-0001-9809-6001
Rosario IglesiasDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0002-5021-1733
Letizia PolitoDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum-University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy.ORCID 0000-0001-8051-4981
Lucía CitoresDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0003-3784-5042
Massimo BortolottiDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum-University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy.ORCID 0000-0001-9030-2237
José M FerrerasDepartment of Biochemistry and Molecular Biology and Physiology, Faculty of Sciences, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0003-4816-5878
Andrea BolognesiDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum-University of Bologna, Via S. Giacomo 14, 40126 Bologna, Italy.ORCID 0000-0001-7497-4586
University of Bologna · ITUniversidad de Valladolid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kirkiin is a new type 2 ribosome-inactivating protein (RIP) purified from the caudex of

Indexed as

Amino Acid SequenceBinding SitesCatalytic DomainMolecular Docking SimulationPassifloraceaePlant ProteinsProtein DomainsRibosome Inactivating Proteins, Type 2RicinSequence Analysis, DNAPlant ProteinsRibosome Inactivating Proteins, Type 2Ricin3D structurecancer therapykirkiinplant toxinprimary sequenceribosome-inactivating proteinricinsugar specificitytoxic lectin

Identifiers

PMID34941700
PMCPMC8705660
OpenAlexW3215814154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.