Evidence map›Paper›PMID 34941689›Full record

ReviewToxins2021

Neglected Venomous Animals and Toxins: Underrated Biotechnological Tools in Drug Development.

Guilherme Rabelo Coelho, Daiane Laise da Silva, Emidio Beraldo-Neto, Hugo Vigerelli, Laudiceia Alves de Oliveira, Juliana Mozer Sciani, Daniel Carvalho Pimenta

Abstract readReview
In one paragraph

Review in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guilherme Rabelo CoelhoLaboratório de Bioquímica, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-9633-7219
Daiane Laise da SilvaLaboratório de Bioquímica, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-8401-7883
Emidio Beraldo-NetoLaboratório de Bioquímica, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-4735-5162
Hugo VigerelliLaboratório de Genética, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0002-8197-2260
Laudiceia Alves de OliveiraLaboratório de Moléstias Infecciosas-Faculdade de Medicina de Botucatu, São Paulo State University (UNESP), São Paulo 01049-010, Brazil.ORCID 0000-0003-3584-2614
Juliana Mozer ScianiLaboratório Multidisciplinar em Pesquisa, Universidade São Francisco, Bragança Paulista 12916-900, Brazil.ORCID 0000-0001-7213-206X
Daniel Carvalho PimentaLaboratório de Bioquímica, Instituto Butantan, São Paulo 05503-900, Brazil.ORCID 0000-0003-2406-0860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the vast repertoire of animal toxins and venoms selected by nature and evolution, mankind opted to devote its scientific attention-during the last century-to a restricted group of animals, leaving a myriad of toxic creatures aside. There are several underlying and justifiable reasons for this, which include dealing with the public health problems caused by envenoming by such animals. However, these studies became saturated and gave rise to a whole group of animals that become neglected regarding their venoms and secretions. This repertoire of unexplored toxins and venoms bears biotechnological potential, including the development of new technologies, therapeutic agents and diagnostic tools and must, therefore, be assessed. In this review, we will approach such topics through an interconnected historical and scientific perspective that will bring up the major discoveries and innovations in toxinology, achieved by researchers from the Butantan Institute and others, and describe some of the major research outcomes from the study of these neglected animals.

Indexed as

Drug DevelopmentAnimalsHumansToxins, BiologicalVenomsToxins, BiologicalVenomsdrug discoveryskin secretiontoxinsvenoms

Identifiers

PMID34941689
PMCPMC8708286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.