Evidence map›Paper›PMID 34940759›Full record

ReviewNon-coding RNA2021

The Role of microRNAs in the Mammary Gland Development, Health, and Function of Cattle, Goats, and Sheep.

Artem P Dysin, Olga Y Barkova, Marina V Pozovnikova

Open access · goldAbstract readReview
In one paragraph

Review in Non-coding RNA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. MicroRNA-30a-3p Influences Milk Fat Metabolism by TargetingAnimals : an open access journal from MDPI · 2025
    Article
  7. Article
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  9. Review
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  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Artem P DysinRussian Research Institute of Farm Animal Genetics and Breeding-Branch of the L. K. Ernst Federal Science Center for Animal Husbandry, Pushkin, 196625 St. Petersburg, Russia.ORCID 0000-0002-4468-0365
Olga Y BarkovaRussian Research Institute of Farm Animal Genetics and Breeding-Branch of the L. K. Ernst Federal Science Center for Animal Husbandry, Pushkin, 196625 St. Petersburg, Russia.
Marina V PozovnikovaRussian Research Institute of Farm Animal Genetics and Breeding-Branch of the L. K. Ernst Federal Science Center for Animal Husbandry, Pushkin, 196625 St. Petersburg, Russia.ORCID 0000-0002-8658-2026
All-Russian Research Institute of Genetics and Farm Animal Breeding · RU

Funding

Russian Science Foundation 21-16-00049
6 · The paper itself

Abstract

Milk is an integral and therefore complex structural element of mammalian nutrition. Therefore, it is simple to conclude that lactation, the process of producing milk, is as complex as the mammary gland, the organ responsible for this biochemical activity. Nutrition, genetics, epigenetics, disease pathogens, climatic conditions, and other environmental variables all impact breast productivity. In the last decade, the number of studies devoted to epigenetics has increased dramatically. Reports are increasingly describing the direct participation of microRNAs (miRNAs), small noncoding RNAs that regulate gene expression post-transcriptionally, in the regulation of mammary gland development and function. This paper presents a summary of the current state of knowledge about the roles of miRNAs in mammary gland development, health, and functions, particularly during lactation. The significance of miRNAs in signaling pathways, cellular proliferation, and the lipid metabolism in agricultural ruminants, which are crucial in light of their role in the nutrition of humans as consumers of dairy products, is discussed.

Indexed as

farm animalslactationmammary glandmiRNA

Identifiers

PMID34940759
PMCPMC8708473
OpenAlexW4200595322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.