Evidence map›Paper›PMID 34940753›Full record

ArticleNeurology international2021

Detecting Incident Delirium within Routinely Collected Inpatient Rehabilitation Data: Validation of a Chart-Based Method.

Marco G Ceppi, Marlene S Rauch, Peter S Sándor, Andreas R Gantenbein, Shyam Krishnakumar, Monika Albert, Christoph R Meier

Open access · goldAbstract read
In one paragraph

Article in Neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Marco G CeppiBasel Pharmacoepidemiology Unit, Department of Pharmaceutical Sciences, Division of Clinical Pharmacy and Epidemiology, University of Basel, 4031 Basel, Switzerland.ORCID 0000-0001-8938-8125
Marlene S RauchBasel Pharmacoepidemiology Unit, Department of Pharmaceutical Sciences, Division of Clinical Pharmacy and Epidemiology, University of Basel, 4031 Basel, Switzerland.
Peter S SándorNeurorehabilitation and Research Department, ZURZACH Care, 5330 Bad Zurzach, Switzerland.
Andreas R GantenbeinNeurorehabilitation and Research Department, ZURZACH Care, 5330 Bad Zurzach, Switzerland.
Shyam KrishnakumarNeurorehabilitation and Research Department, ZURZACH Care, 5330 Bad Zurzach, Switzerland.
Monika AlbertNeurorehabilitation and Research Department, ZURZACH Care, 5330 Bad Zurzach, Switzerland.
Christoph R MeierBasel Pharmacoepidemiology Unit, Department of Pharmaceutical Sciences, Division of Clinical Pharmacy and Epidemiology, University of Basel, 4031 Basel, Switzerland.
University of Basel · CHStiftung für Forschung in Spätantike und Mittelalter HR. Sennhauser · CHUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelirium is a brain condition associated with poor outcomes in rehabilitation. It is therefore important to assess delirium incidence in rehabilitation. PURPOSE: To develop and validate a chart-based method to identify incident delirium episodes within the electronic database of a Swiss rehabilitation clinic, and to identify a study population of validated incident delirium episodes for further research purposes.

designRetrospective validation study. SETTINGS: Routinely collected inpatient clinical data from ZURZACH Care.

participantsAll patients undergoing rehabilitation at ZURZACH Care, Rehaklinik Bad Zurzach between 2015 and 2018 were included.

methodsWithin the study population, we identified all rehabilitation stays for which ≥2 delirium-predictive key words (common terms used to describe delirious patients) were recorded in the medical charts. We excluded all prevalent delirium episodes and defined the remaining episodes to be potentially incident. At least two physicians independently confirmed or refuted each potential incident delirium episode by reviewing the patient charts. We calculated the positive predictive value (PPV) with 95% confidence interval (95% CI) for all potential incident delirium episodes and for specific subgroups.

resultsWithin 10,515 rehabilitation stays we identified 554 potential incident delirium episodes. Overall, 125 potential incident delirium episodes were confirmed by expert review. The PPV of the chart-based method varied from 0.23 (95% CI 0.19-0.26) overall to 0.69 (95% CI 0.56-0.79) in specific subgroups.

conclusionsOur chart-based method was able to capture incident delirium episodes with low to moderate accuracy. By conducting an additional expert review of the medical charts, we identified a study population of validated incident delirium episodes. Our chart-based method contributes towards an automated detection of potential incident delirium episodes that, supplemented with expert review, efficiently yields a validated population of incident delirium episodes for research purposes.

Indexed as

deliriumneurocognitive disorderspatient-generated health datarehabilitationvalidation study

Identifiers

PMID34940753
PMCPMC8705493
OpenAlexW4200227139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.