Evidence map›Paper›PMID 34940711›Full record

ArticleMarine drugs2021

Protective Effect of Flavonoids from a Deep-Sea-Derived

Jia-Rong Hou, Yan-Hong Wang, Ying-Nan Zhong, Tong-Tong Che, Yang Hu, Jie Bao, Ning Meng

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Endothelial-Protective Actions of Diethylether Extract fromInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Review
  7. Peptides fromACS omega · 2023
    Article
  8. Review
  9. Marine drugs · 2022
    Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jia-Rong HouDepartment of Biotechnology, School of Biological Science and Technology, University of Jinan, Jinan 250022, China.
Yan-Hong WangDepartment of Biotechnology, School of Biological Science and Technology, University of Jinan, Jinan 250022, China.
Ying-Nan ZhongDepartment of Biotechnology, School of Biological Science and Technology, University of Jinan, Jinan 250022, China.
Tong-Tong CheDepartment of Biotechnology, School of Biological Science and Technology, University of Jinan, Jinan 250022, China.
Yang HuDepartment of Biotechnology, School of Biological Science and Technology, University of Jinan, Jinan 250022, China.
Jie BaoDepartment of Biotechnology, School of Biological Science and Technology, University of Jinan, Jinan 250022, China.
Ning MengDepartment of Biotechnology, School of Biological Science and Technology, University of Jinan, Jinan 250022, China.
University of Jinan · CN

Funding

National Natural Science Foundation of China 31671214Natural Science Foundation of Shandong Province ZR2020YQ52, ZR2020MD091, ZR2019PC051Open Fund of Joint LMB, LMM and LAMB LMB20201007Project of Shandong Province Higher Educational Youth Innovation Science and Technology Program 2020KJE006Science and Technology Project of University of Jinan XKY1517
6 · The paper itself

Abstract

Oxidized low-density lipoprotein (ox-LDL)-induced oxidative injury in vascular endothelial cells is crucial for the progression of cardiovascular diseases, including atherosclerosis. Several flavonoids have been shown cardiovascular protective effects. Recently, our research group confirmed that the novel flavonoids isolated from the deep-sea-derived fungus

Indexed as

AscomycotaAnimalsAntioxidantsAquatic OrganismsEndothelium, VascularFlavonoidsHeme Oxygenase-1HumansLipoproteins, LDLNF-E2-Related Factor 2Oxidative StressProto-Oncogene Proteins c-aktAntioxidantsFlavonoidsHeme Oxygenase-1Lipoproteins, LDLNFE2L2 protein, humanNF-E2-Related Factor 2Proto-Oncogene Proteins c-aktapoptosisflavonoidNrf2oxidized low-density lipoproteinvascular endothelial cell

Identifiers

PMID34940711
PMCPMC8707590
OpenAlexW4200555669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.