Evidence map›Paper›PMID 34940701›Full record

ArticleMarine drugs2021

Anti-Inflammatory Activity of Fucoidan Extracts In Vitro.

Tauseef Ahmad, Mathew Suji Eapen, Muhammad Ishaq, Ah Young Park, Samuel S Karpiniec, Damien N Stringer, Sukhwinder Singh Sohal, J Helen Fitton, Nuri Guven, Vanni Caruso and 1 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Fucoidan fromResearch and reports in urology · 2026
    Trial
  3. Article
  4. Review
  5. Low-Molecular-Weight Fucoidan fromFoods (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Fucoidan Oligosaccharides fromMarine drugs · 2026
    Article
  10. From Sea to Cell:Marine drugs · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Tauseef AhmadSchool of Health Sciences, University of Tasmania, Launceston, TAS 7248, Australia.ORCID 0000-0001-5322-9413
Mathew Suji EapenRespiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, TAS 7248, Australia.ORCID 0000-0003-0570-7059
Muhammad IshaqSchool of Pharmacy and Pharmacology, University of Tasmania, Hobart, TAS 7005, Australia.ORCID 0000-0002-4498-7930
Ah Young ParkMarinova Pty Ltd., Cambridge, TAS 7170, Australia.ORCID 0000-0002-5212-4369
Samuel S KarpiniecMarinova Pty Ltd., Cambridge, TAS 7170, Australia.
Damien N StringerMarinova Pty Ltd., Cambridge, TAS 7170, Australia.ORCID 0000-0003-2217-491X
Sukhwinder Singh SohalRespiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, TAS 7248, Australia.
J Helen FittonMarinova Pty Ltd., Cambridge, TAS 7170, Australia.ORCID 0000-0002-1402-0809
Nuri GuvenSchool of Pharmacy and Pharmacology, University of Tasmania, Hobart, TAS 7005, Australia.ORCID 0000-0003-3782-767X
Vanni CarusoSchool of Pharmacy and Pharmacology, University of Tasmania, Hobart, TAS 7005, Australia.ORCID 0000-0002-0523-6149
Rajaraman EriSchool of Health Sciences, University of Tasmania, Launceston, TAS 7248, Australia.ORCID 0000-0003-1688-8043
University of Tasmania · AU

Funding

Marinova Pty Ltd, Australia 00003944
6 · The paper itself

Abstract

Fucoidans are sulfated, complex, fucose-rich polymers found in brown seaweeds. Fucoidans have been shown to have multiple bioactivities, including anti-inflammatory effects, and are known to inhibit inflammatory processes via a number of pathways such as selectin blockade and enzyme inhibition, and have demonstrated inhibition of inflammatory pathologies

Indexed as

SeaweedAnimalsAnti-Inflammatory AgentsAquatic OrganismsHumansInterleukin-1Interleukin-6Leukocytes, MononuclearMacrophagesPlant ExtractsPolysaccharidesTumor Necrosis Factor-alphaAnti-Inflammatory AgentsfucoidanInterleukin-1Interleukin-6Plant ExtractsPolysaccharidesTumor Necrosis Factor-alphaAscophyllum nodosumfucoidanFucus vesiculosusLaminaria japonicaMacrocystis pyriferaPBMCsTHP-1TNF-α, IL-1β, and IL-6Undaria pinnatifida

Identifiers

PMID34940701
PMCPMC8704339
OpenAlexW4200430220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.