Evidence map›Paper›PMID 34940668›Full record

ArticleMarine drugs2021

On the Path to Thermo-Stable Collagen: Culturing the Versatile Sponge

Boaz Orel, Marco Giovine, Micha Ilan

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Collagen from Marine Sources for Potential Application in Wound Treatment.Progress in molecular and subcellular biology · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Boaz OrelSchool of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel.
Marco GiovineDepartment of Sciences of Earth, Environment and Life, University of Genoa, Corso Europa 26, 16132 Genoa, Italy.ORCID 0000-0001-8085-0619
Micha IlanSchool of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 6997801, Israel.ORCID 0000-0002-4188-4573
Tel Aviv University · ILUniversity of Genoa · IT

Funding

Ministero degli Affari Esteri Italian-Israeli Scientific track, project SMARTEXMinistry of Science and Technology Italian-Israeli Scientific track, project SMARTEX
6 · The paper itself

Abstract

The collagen proteins family is sought-after in the pharmaceuticals, cosmetics, and food industries for various biotechnological applications. The most abundant sources of collagen are pigs and cows, but due to religious restrictions and possible disease transmission, they became less attractive. An alternative source can be found in marine invertebrates, specifically in sponges. Alas, two problems arise: (1). Growing sponges is complicated. (2). Sponge collagen has low heat tolerance, which can impose a problem for human biotechnological usage. To fill these gaps, we studied the collagen-abundant sponge

Indexed as

PoriferaAnimalsAquatic OrganismsCollagenTemperatureCollagencollagencultureLevantmesophoticPoriferatemperature effecttransplantation

Identifiers

PMID34940668
PMCPMC8703642
OpenAlexW3217471805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.