Evidence map›Paper›PMID 34940616›Full record

ArticleMetabolites2021

Physical Activity and Dietary Composition Relate to Differences in Gut Microbial Patterns in a Multi-Ethnic Cohort-The HELIUS Study.

Veera Houttu, Ulrika Boulund, Mary Nicolaou, Adriaan Georgius Holleboom, Aldo Grefhorst, Henrike Galenkamp, Bert-Jan van den Born, Koos Zwinderman, Max Nieuwdorp

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The gut microbiome connects nutrition and human health.Nature reviews. Gastroenterology & hepatology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Veera HouttuDepartment of Vascular Medicine, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-6430-7007
Ulrika BoulundDepartment of Vascular Medicine, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Mary NicolaouDepartment of Public and Occupational Health, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Adriaan Georgius HolleboomDepartment of Vascular Medicine, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Aldo GrefhorstDepartment of Vascular Medicine, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Henrike GalenkampDepartment of Public and Occupational Health, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Bert-Jan van den BornDepartment of Vascular Medicine, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Koos ZwindermanDepartment of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Max NieuwdorpDepartment of Vascular Medicine, Amsterdam UMC, Location AMC at University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NL

Funding

the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 813781 ITN BestTreat
6 · The paper itself

Abstract

Physical activity (PA) at recommended levels contributes to the prevention of non-communicable diseases, such as atherosclerotic cardiovascular disease (asCVD) and type 2 diabetes mellitus (T2DM). Since the composition of the gut microbiota is strongly intertwined with dietary intake, the specific effect of exercise on the gut microbiota is not known. Moreover, multiple other factors, such as ethnicity, influence the composition of the gut microbiota, and this may be derived by distinct diet as well as PA patterns. Here we aim to untangle the associations between PA and the gut microbiota in a sample (

Indexed as

calf circumferencecreatininecreatinine kinasecross-sectionaldietgut microbiotamulti-ethnic populationmuscle strengthphysical activitythe HELIUS study

Identifiers

PMID34940616
PMCPMC8707449
OpenAlexW4200046976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.