Evidence map›Paper›PMID 34940554›Full record

ReviewJournal of functional biomaterials2021

Quantum Dots: Synthesis, Antibody Conjugation, and HER2-Receptor Targeting for Breast Cancer Therapy.

Iqra Fatima, Abbas Rahdar, Saman Sargazi, Mahmood Barani, Mohadeseh Hassanisaadi, Vijay Kumar Thakur

Open access · goldAbstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 68 citations in OpenAlex.

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  9. Nanocarriers for cutting-edge cancer immunotherapies.Journal of translational medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

Iqra FatimaDepartment of Pharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Abbas RahdarDepartment of Physics, University of Zabol, Zabol 98613-35856, Iran.ORCID 0000-0003-4766-9214
Saman SargaziCellular and Molecular Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan 98167-43463, Iran.ORCID 0000-0002-2255-5977
Mahmood BaraniMedical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman 76169-13555, Iran.ORCID 0000-0002-1711-2522
Mohadeseh HassanisaadiMedical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman 76169-13555, Iran.
Vijay Kumar ThakurBiorefining and Advanced Materials Research Center, SRUC, Edinburgh EH9 3JG, UK.ORCID 0000-0002-0790-2264
Kerman University of Medical Sciences · IRQuaid-i-Azam University · PKShahid Bahonar University of Kerman · IRUniversity of Petroleum and Energy Studies · INZabol University · IRZahedan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is becoming one of the main lethal carcinomas in the recent era, and its occurrence rate is increasing day by day. There are different breast cancer biomarkers, and their overexpression takes place in the metastasis of cancer cells. The most prevalent breast cancer biomarker is the human epidermal growth factor receptor2 (HER2). As this biomarker is overexpressed in malignant breast tissues, it has become the main focus in targeted therapies to fight breast cancer. There is a cascade of mechanisms involved in metastasis and cell proliferation in cancer cells. Nanotechnology has become extremely advanced in targeting and imaging cancerous cells. Quantum dots (QDs) are semiconductor NPs, and they are used for bioimaging, biolabeling, and biosensing. They are synthesized by different approaches such as top-down, bottom-up, and synthetic methods. Fully human monoclonal antibodies synthesized using transgenic mice having human immunoglobulin are used to target malignant cells. For the HER2 receptor, herceptin

Indexed as

breast cancerHER2 receptormonoclonal antibodiesquantum dot–antibody conjugatequantum dots

Identifiers

PMID34940554
PMCPMC8708439
OpenAlexW4200474294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.