Evidence map›Paper›PMID 34940524›Full record

ArticleJournal of cardiovascular development and disease2021

Long-Term Survival in Patients with Post-Operative Atrial Fibrillation after Cardiac Surgery: Analysis from a Prospective Cohort Study.

Jacopo Marazzato, Sergio Masnaghetti, Roberto De Ponti, Paolo Verdecchia, Federico Blasi, Sandro Ferrarese, Monica Trapasso, Antonio Spanevello, Fabio Angeli

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jacopo MarazzatoDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
Sergio MasnaghettiDepartment of Medicine and Cardiopulmonary Rehabilitation, Maugeri Care and Research Institute, IRCCS, 21049 Tradate, Italy.
Roberto De PontiDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.ORCID 0000-0003-3278-1721
Paolo VerdecchiaFondazione Umbra Cuore e Ipertensione-ONLUS and Division of Cardiology, Hospital Santa Maria della Misericordia, 06100 Perugia, Italy.
Federico BlasiDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
Sandro FerrareseDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
Monica TrapassoDipartimento di Igiene e Prevenzione Sanitaria, PSAL, Sede Territoriale di Varese, ATS Insubria, 21100 Varese, Italy.
Antonio SpanevelloDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
Fabio AngeliDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.ORCID 0000-0003-4925-7985
University of Insubria · ITIstituti Clinici Scientifici Maugeri · ITOspedale Santa Maria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-operative (POP) atrial fibrillation (AF) is frequent in patients who undergo cardiac surgery. However, its prognostic impact in the long term remains unclear.

methodsWe followed 1386 patients who underwent cardiac surgery for an average of 10 ± 3 years. According to clinical history of AF before and after surgery, four subgroups were identified: (1) patients with no history of AF and without episodes of AF during the first 30 days after surgery (control or Group 1, n = 726), (2) patients with no history of AF before surgery in whom new-onset POP AF was detected during the first 30 days after surgery (new-onset POP AF or Group 2, n = 452), (3) patients with a history of paroxysmal/persistent AF before cardiac surgery (Group 3, n = 125, including 87 POP AF patients and 38 who did not develop POP AF), and (4) patients with permanent AF at the time of cardiac surgery (Group 4, n = 83). All-cause mortality was the primary outcome of the study. We tested the associations of potential determinants with all-cause mortality using univariable and multivariable statistical analyses.

resultsOverall, 473 patients (34%) died during follow-up. After adjustment for multiple confounders, new-onset POP AF (hazard ratio (HR) = 1.31, 95% confidence interval (CI): 0.90-1.89;

conclusionsIn this cohort of patients who underwent different types of heart surgery, POP AF was not associated with an increased risk of mortality. In this setting, the role of long-term anticoagulation remains unclear.

Indexed as

atrial fibrillationcardiac surgerychronic diseaseoral anticoagulationpost-operative atrial fibrillation

Identifiers

PMID34940524
PMCPMC8707624
OpenAlexW3215971030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.