Evidence map›Paper›PMID 34940378›Full record

ReviewBioengineering (Basel, Switzerland)2021

Current Therapeutics and Future Perspectives to Ocular Melanocytic Neoplasms in Dogs and Cats.

Tarcísio Guerra Guimarães, Karla Menezes Cardoso, Pedro Tralhão, Carlos Miguel Marto, Nuno Alexandre, Maria Filomena Botelho, Mafalda Laranjo

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Adjuvant electrochemotherapy of malignant ocular melanoma in a dog.Veterinary research forum : an international quarterly journal · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tarcísio Guerra GuimarãesInstitute of Research and Advanced Training (IIFA), University of Évora, 7002-554 Évora, Portugal.ORCID 0000-0003-4547-3891
Karla Menezes CardosoInstitute of Research and Advanced Training (IIFA), University of Évora, 7002-554 Évora, Portugal.
Pedro TralhãoCenter of Veterinary Ophthalmology, Oftalvet, 4050-102 Porto, Portugal.
Carlos Miguel MartoInstitute of Biophysics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-9269-5417
Nuno AlexandreMediterranean Institute for Agriculture, Environment and Development (MED), University of Évora, 7006-554 Évora, Portugal.
Maria Filomena BotelhoInstitute of Biophysics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-7202-1650
Mafalda LaranjoInstitute of Biophysics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-0689-6007
University of Coimbra · PTUniversity of Évora · PT

Funding

Fundação para a Ciência e Tecnologia SFRH/BD/139319/2018Fundação para a Ciência e Tecnologia Strategic Projects UID/NEU/04539/2019, UIDB/04539/2020, UIDP/04539/2020, and by COMPETE-FEDER (POCI-01-0145-FEDER-007440)
6 · The paper itself

Abstract

Neoplasms of melanocytic origin are diseases relevant to dogs and cats' ophthalmic oncology due to their incidence, potential visual loss, and consequent decrease in life quality and expectancy. Despite its non-specific clinical presentation, melanocytic neoplasms can be histologically distinguished in melanocytomas, which present benign characteristics, and malignant melanomas. The diagnosis often occurs in advanced cases, limiting the therapeutic options. Surgery, cryotherapy, radiotherapy, photodynamic therapy (PDT), and laser are currently available therapeutic strategies. As no clinical guidelines are available, the treatment choice is primarily based on the clinician's preference, proficiency, and the owner's financial constraints. While surgery is curative in benign lesions, ocular melanomas present a variable response to treatments, besides the potential of tumour recurrences or metastatic disease. This review presents the currently available therapies for ocular melanocytic neoplasms in dogs and cats, describing the therapeutic, indications, and limitations. Additionally, new therapeutics being developed are presented and discussed, as they can improve the current treatment options.

Indexed as

melanocytic neoplasmsmelanomatherapeutics

Identifiers

PMID34940378
PMCPMC8698280
OpenAlexW4200089585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.