Evidence map›Paper›PMID 34940373›Full record

ReviewBioengineering (Basel, Switzerland)2021

Is Culture Expansion Necessary in Autologous Mesenchymal Stromal Cell Therapy to Obtain Superior Results in the Management of Knee Osteoarthritis?-Meta-Analysis of Randomized Controlled Trials.

Sathish Muthu, Randhi Rama Kartheek, Naveen Jeyaraman, Ramya Lakshmi Rajendran, Manish Khanna, Madhan Jeyaraman, Rathinavelpandian Perunchezhian Packkyarathinam, Prakash Gangadaran, Byeong-Cheol Ahn

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Stromal vascular fraction therapy for knee osteoarthritis: a systematic review.Therapeutic advances in musculoskeletal disease · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Sathish MuthuDepartment of Orthopaedics, Government Medical College and Hospital, Dindigul 624001, Tamil Nadu, India.ORCID 0000-0002-7143-4354
Randhi Rama KartheekIndian Stem Cell Study Group (ISCSG) Association, Lucknow 226010, Uttar Pradesh, India.
Naveen JeyaramanIndian Stem Cell Study Group (ISCSG) Association, Lucknow 226010, Uttar Pradesh, India.ORCID 0000-0002-4362-3326
Ramya Lakshmi RajendranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Korea.ORCID 0000-0001-6987-0854
Manish KhannaIndian Stem Cell Study Group (ISCSG) Association, Lucknow 226010, Uttar Pradesh, India.
Madhan JeyaramanDepartment of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida 201310, Uttar Pradesh, India.ORCID 0000-0002-9045-9493
Rathinavelpandian Perunchezhian PackkyarathinamIndian Stem Cell Study Group (ISCSG) Association, Lucknow 226010, Uttar Pradesh, India.ORCID 0000-0003-4820-5278
Prakash GangadaranDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Korea.ORCID 0000-0002-0658-4604
Byeong-Cheol AhnDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu 41944, Korea.ORCID 0000-0001-7700-3929
Kyungpook National University Hospital · KRDr. Ram Manohar Lohia National Law University · INDr. M.G.R. Educational and Research Institute · INGovernment Medical College · INGovernment Medical College and Hospital · INInstitute of Medical Sciences · IN

Funding

National Research Foundation of Korea NRF-2019R1I1A1A01061296National Research Foundation of Korea NRF-2021R1I1A1A01040732
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adipose-derived mesenchymal stromal cellbone-marrow derived mesenchymal stromal cellcartilage regenerationcultureknee osteoarthritismesenchymal stromal cellmeta-analysis

Identifiers

PMID34940373
PMCPMC8698637
OpenAlexW4200064655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.