Evidence map›Paper›PMID 34940352›Full record

ArticleBioengineering (Basel, Switzerland)2021

Biocompatible Customized 3D Bone Scaffolds Treated with CRFP, an Osteogenic Peptide.

Vamiq M Mustahsan, Amith Anugu, David E Komatsu, Imin Kao, Srinivas Pentyala

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vamiq M MustahsanDepartment of Anesthesiology, Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0003-4149-322X
Amith AnuguDepartment of Anesthesiology, Stony Brook University, Stony Brook, NY 11794, USA.
David E KomatsuDepartment of Orthopedics, Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0002-2618-9492
Imin KaoDepartment of Mechanical Engineering, Stony Brook University, Stony Brook, NY 11794, USA.
Srinivas PentyalaDepartment of Anesthesiology, Stony Brook University, Stony Brook, NY 11794, USA.
Stony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently used synthetic bone graft substitutes (BGS) are either too weak to bear the principal load or if metallic, they can support loading, but can lead to stress shielding and are unable to integrate fully. In this study, we developed biocompatible, 3D printed scaffolds derived from µCT images of the bone that can overcome these issues and support the growth of osteoblasts.

methodsCylindrical scaffolds were fabricated with acrylonitrile butadiene styrene (ABS) and Stratasys

resultsFor the ABS scaffolds, there was a 9.8% increase in compressive strength (

conclusionsMED610 scaffolds are excellent BGS as they support osteoblast growth and show enhanced bone growth with enhanced compressive strength when augmented with CRFP.

Indexed as

3D printingABSartificial boneCRFPMED610osteogenic peptidescaffolds

Identifiers

PMID34940352
PMCPMC8698998
OpenAlexW3215218591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.