Evidence map›Paper›PMID 34940343›Full record

ArticleBioengineering (Basel, Switzerland)2021

Preclinical Efficacy of Pro- and Anti-Angiogenic Peptide Hydrogels to Treat Age-Related Macular Degeneration.

Amanda Acevedo-Jake, Siyu Shi, Zain Siddiqui, Sreya Sanyal, Rebecca Schur, Simon Kaja, Alex Yuan, Vivek A Kumar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Amanda Acevedo-JakeDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.
Siyu ShiStanford School of Medicine, Stanford University, Stanford, CA 94305, USA.
Zain SiddiquiDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.
Sreya SanyalDepartment of Biology, New Jersey Institute of Technology, Newark, NJ 07102, USA.
Rebecca SchurCole Eye Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, OH 44195, USA.
Simon KajaResearch & Development Division, Experimentica Ltd., 70211 Kuopio, Finland.
Alex YuanCole Eye Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, OH 44195, USA.
Vivek A KumarDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.ORCID 0000-0001-7536-9281
New Jersey Institute of Technology · USCleveland Clinic Lerner College of Medicine · USLoyola University Chicago · USRutgers, The State University of New Jersey · USStanford University · US

Funding

National Institute of Health EY029504National Science Foundation 1903617
6 · The paper itself

Abstract

Pro-angiogenic and anti-angiogenic peptide hydrogels were evaluated against the standard of care wet age-related macular degeneration (AMD) therapy, Aflibercept (Eylea

Indexed as

anti-angiogenicbiomaterialshydrogelmulti-functional scaffoldspro-angiogenictissue regenerationwet age-related macular degeneration

Identifiers

PMID34940343
PMCPMC8698576
OpenAlexW3214891591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.