Evidence map›Paper›PMID 34940301›Full record

ArticleGels (Basel, Switzerland)2021

New Hydrogel Network Based on Alginate and a Spiroacetal Copolymer.

Alina Elena Sandu, Loredana Elena Nita, Aurica P Chiriac, Nita Tudorachi, Alina Gabriela Rusu, Daniela Pamfil

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alina Elena Sandu"PetruPoni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41-A, RO-700487 Iasi, Romania.
Loredana Elena Nita"PetruPoni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41-A, RO-700487 Iasi, Romania.
Aurica P Chiriac"PetruPoni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41-A, RO-700487 Iasi, Romania.ORCID 0000-0002-8452-1780
Nita Tudorachi"PetruPoni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41-A, RO-700487 Iasi, Romania.
Alina Gabriela Rusu"PetruPoni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41-A, RO-700487 Iasi, Romania.ORCID 0000-0002-8913-7446
Daniela Pamfil"PetruPoni" Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley 41-A, RO-700487 Iasi, Romania.

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii 339PED⁄2020, PN-III-P2-2.1-PED-2019- 2743
6 · The paper itself

Abstract

This study reports a strategy for developing a biohybrid complex based on a natural/synthetic polymer conjugate as a gel-type structure. Coupling synthetic polymers with natural compounds represents an important approach to generating gels with superior properties and with potential for biomedical applications. The study presents the preparation of hybrid gels with tunable characteristics by using a spiroacetal polymer and alginate as co-partners in different ratios. The new network formation was tested, and the structure was confirmed by FTIR and SEM techniques. The physical properties of the new gels, namely their thermal stability and swelling behavior, were investigated. The study showed that the increase in alginate content caused a smooth increase in thermal stability due to the additional crosslinking bridges that appeared. Moreover, increasing the content of the synthetic polymer in the structure of the gel network ensures a slower release of carvacrol, the encapsulated bioactive compound.

Indexed as

alginatebio-applicationshybrid gel networknatural/synthetic polymer conjugatepoly(itaconic anhydride-co-3,9-divinyl-2,4,8,10-tetra-oxa-spiro[5.5]undecane)

Identifiers

PMID34940301
PMCPMC8701164

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.