Evidence map›Paper›PMID 34940092›Full record

SynthesisCurrent oncology (Toronto, Ont.)2021

Treatment Algorithm in Cancer-Associated Thrombosis: Updated Canadian Expert Consensus.

Marc Carrier, Normand Blais, Mark Crowther, Petr Kavan, Grégoire Le Gal, Otto Moodley, Sudeep Shivakumar, Deepa Suryanarayan, Vicky Tagalakis, Cynthia Wu and 1 more

Open access · goldAbstract readSystematic ReviewConsensus Statement
In one paragraph

Synthesis in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
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  9. Review
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  16. Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2023
    Article
  17. Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2023
    Article
  18. Review
  19. The 5 most frequently asked questions about factor Xa inhibitors.Hematology. American Society of Hematology. Education Program · 2022
    Article
  20. [Cancer-associated coagulation disorders].Dermatologie (Heidelberg, Germany) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Marc CarrierDepartment of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0001-8296-2972
Normand BlaisDepartment of Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, QC H2L 4M1, Canada.ORCID 0000-0003-2698-4362
Mark CrowtherDepartment of Medicine, McMaster University, Hamilton, ON L8N 4A6, Canada.
Petr KavanDepartment of Oncology, Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada.
Grégoire Le GalDepartment of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, Canada.ORCID 0000-0002-9253-248X
Otto MoodleyDepartment of Hematology, Royal University Hospital, Saskatoon, SK S7N 0W8, Canada.
Sudeep ShivakumarDepartment of Medicine, QEII Health Sciences Centre, Dalhousie University, Halifax, NS B3H 3A7, Canada.
Deepa SuryanarayanDepartment of Medicine, University of Calgary, Foothills Hospital, Calgary, AB T2N 2T9, Canada.
Vicky TagalakisDepartment of Medicine, Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Montreal, QC H3T 1E2, Canada.
Cynthia WuDepartment of Medicine, University of Alberta, Edmonton, AB T5J 2J7, Canada.
Agnes Y Y LeeDepartment of Medicine, University of British Columbia, British Columbia Cancer Agency, Vancouver, BC V5Z 4E6, Canada.
Jewish General Hospital · CAUniversity of Ottawa · CABC Cancer Agency · CACentre Hospitalier de l’Université de Montréal · CADalhousie University · CAMcMaster University · CARoyal University Hospital · CAUniversity of Alberta · CAUniversity of Calgary · CA

Funding

Bayer (Canada) Thrombosis CanadaLeo Pharma (United States) Thrombosis CanadaPfizer (Canada) Thrombosis CanadaServier (Canada) Thrombosis Canada
6 · The paper itself

Abstract

Patients with cancer-associated thrombosis (CAT) are at high risk of recurrent venous thromboembolism (VTE) and major bleeding complications. Risks vary significantly between individuals based on cancer status, treatment, and other characteristics. To facilitate the evidence-based management of anticoagulant therapy in this patient population, a committee of 11 Canadian clinical experts updated a consensus-based algorithm for the acute and extended treatment of symptomatic and incidental CAT that was developed in 2018. Following a systematic review of the literature, updates to the algorithm were discussed during an online teleconference, and the algorithm was subsequently refined based on feedback from committee members. Clinicians using this treatment algorithm should consider bleeding risk, type of cancer, and drug-drug interactions, as well as patient and clinician preferences, in tailoring anticoagulation for patients with CAT. Anticoagulant therapy should be adapted as the patient's cancer status and management change over time.

Indexed as

NeoplasmsThrombosisAlgorithmsCanadaConsensusHumansanticoagulationcancer-associated thrombosispulmonary embolismvenous thromboembolism

Identifiers

PMID34940092
PMCPMC8700468
OpenAlexW4200369908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.