ArticleDentistry journal2021
A Radical-Free Approach to Teeth Whitening.
Article in Dentistry journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Effects of phthalimidoperoxycaproic acid (PAP+) associated or not with LED irradiation as a bleaching agent: an in vitro study.Lasers in medical science · 2026Article
- Phthalimidoperoxycaproic Acid (PAP) Versus Peroxides and Impact on Dental Enamel After Whitening Treatment: An In Vitro Study.Journal of functional biomaterials · 2026Article
- Tooth-whitening treatment with potassium sodium tartrate: a non-invasive method that preserves enamel integrity.BDJ open · 2026Article
- Tooth-Whitening Agents and Polymer-Based Carriers: Efficacy, Safety, and Clinical Perspectives.Polymers · 2025Review
- Hydrogen Peroxide-Free Color Correctors for Tooth Whitening in Adolescents and Young Adults: A Systematic Review of In Vitro and Clinical Evidence.Dentistry journal · 2025Review
- An Evaluation of the Efficacy of a Novel Non-Peroxide, Phthalimidoperoxycaproic Acid Teeth Whitening Agent in Conjunction with 810-nm Diode Laser.Journal of pharmacy & bioallied sciences · 2025Article
- Peroxide-Free Titanium Dioxide Nanoparticle-Based Photocatalytic Bleaching: In Vitro Study on Bovine Teeth.BioMed research international · 2025Article
- Safety and Effectiveness of a Novel Color Corrector Serum for Causing Temporary Changes to Tooth Shade: A Randomized Controlled Clinical Study.Dentistry journal · 2024Article
- Evaluating the efficiency of two different over-the-counter tooth whitening systems: a randomised controlled clinical trial.BDJ open · 2024Article
- Effects of Time-Elapsed Bleaching on the Surface and Mechanical Properties of Dentin Substrate Using Hydrogen Peroxide-Free Nanohydroxyapatite Gel.International journal of nanomedicine · 2024Article
- Tooth-Whitening with a Novel Phthalimido Peroxy Caproic Acid: Short Communication.Clinical, cosmetic and investigational dentistry · 2024Article
- Effectiveness and Safety of Over-the-Counter Tooth-Whitening Agents Compared to Hydrogen Peroxide In Vitro.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraditional bleaching agents based on hydrogen peroxide (HP) or carbamide peroxide (CP) have adverse soft and hard tissue effects.
objectivesThis study tested a novel formulation of phthalimidoperoxycaproic acid (PAP) with additives to optimise its safety and effectiveness.
methodsA novel gel (PAP+) was formulated. Laboratory studies assessed effects of six 10-minute exposures to PAP+ vs. commercial CP and HP gels, using surface profilometry and microhardness. The effectiveness of PAP+ in vitro against complex polyphenol stains on enamel was compared to 6% HP.
resultsUnlike HP gels, PAP+ gel did not erode enamel. Unlike both CP and HP gels, PAP+ gel did not reduce the surface microhardness of enamel. PAP+ gel on used on polyphenol stains was superior to 6% HP. In this model, six repeated 10-minute treatments with PAP+ gel could improve the shade by approximately eight VITA
conclusionsThese laboratory results support the safety and effectiveness of this new PAP formula and its use as an alternative to CP and HP with superior safety and effectiveness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.