Evidence map›Paper›PMID 34940028›Full record

ReviewDiseases (Basel, Switzerland)2021

Cardiotoxicity and Chemotherapy-The Role of Precision Medicine.

Thyla Viswanathan, Chim C Lang, Russell D Petty, Mark A Baxter

Abstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thyla ViswanathanDundee School of Medicine, Ninewells Hospital, University of Dundee, Dundee DD2 1SY, UK.
Chim C LangDivision of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee DD2 1SY, UK.
Russell D PettyDivision of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee DD2 1SY, UK.
Mark A BaxterDivision of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee DD2 1SY, UK.

Funding

Chief Scientist Office CAF/20/01Medical Research Council MR/T018186/1
6 · The paper itself

Abstract

Cancer and cardiovascular disease are the leading causes of death in the United Kingdom. Many systemic anticancer treatments are associated with short- and long-term cardiotoxicity. With improving cancer survival and an ageing population, identifying those patients at the greatest risk of cardiotoxicity from their cancer treatment is becoming a research priority and has led to a new subspecialty: cardio-oncology. In this concise review article, we discuss cardiotoxicity and systemic anticancer therapy, with a focus on chemotherapy. We also discuss the challenge of identifying those at risk and the role of precision medicine as we strive for a personalised approach to this clinical scenario.

Indexed as

cancer therapycardio-oncologycardiotoxicityheart failurepharmacogeneticsprecision medicine

Identifiers

PMID34940028
PMCPMC8699963

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.