ArticleDiseases (Basel, Switzerland)2021
Ageing and Obesity Shared Patterns: From Molecular Pathogenesis to Epigenetics.
Article in Diseases (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Postbiotics as Emerging Strategy Targeting Obesity- and Aging-Related Breast Cancer-Prospects in Prophylaxis and Therapy.Life (Basel, Switzerland) · 2026Review
- Factors Associated With Physiological Dysregulation Among US Adults Aged 45 Years and Older: A Nationally Representative Study.Journal of aging research · 2026Article
- Review
- Epigenetic Age in Prader-Willi Syndrome and Essential Obesity: A Comparison with Chronological and Vascular Ages.Journal of clinical medicine · 2025Article
- The role of autoantibodies in bridging obesity, aging, and immunosenescence.Immunity & ageing : I & A · 2024Review
- Anti-obesity and immunomodulatory effects of oil and fermented extract dried fromAnimal cells and systems · 2024Article
- Obesity accelerates age defects in B cells, and weight loss improves B cell function.Immunity & ageing : I & A · 2023Article
- Secreted Protein Acidic and Rich in Cysteine (Diseases (Basel, Switzerland) · 2023Article
- DNA Damage as a Mechanistic Link between Air Pollution and Obesity?Medicines (Basel, Switzerland) · 2022Article
- Mapping Genetics and Epigenetics to Explore the Pathways beyond the Correlated Ageing Phenotype.Genes · 2022Article
- Several areas of overlap between obesity and aging indicate obesity as a biomarker of accelerated aging of human B cell function and antibody responses.Immunity & ageing : I & A · 2022Article
- Tricking the Brain with Leptin to Limit Post Liposuction and Post Bariatric Surgery Weight Regain?Diseases (Basel, Switzerland) · 2022Article
- In Vitro Mimicking of Obesity-Induced Biochemical Environment to Study Obesity Impacts on Cells and Tissues.Diseases (Basel, Switzerland) · 2022Article
- Effect of a 3-Week Multidisciplinary Body Weight Reduction Program on the Epigenetic Age Acceleration in Obese Adults.Journal of clinical medicine · 2022Article
- Article
- Article
- Secreted Protein Acidic and Rich in Cysteine (Metabolites · 2022Article
- Exercise, Diet and Sleeping as Regenerative Medicine Adjuvants: Obesity and Ageing as Illustrations.Medicines (Basel, Switzerland) · 2022Review
- Obesity Accelerates Age Defects in Human B Cells and Induces Autoimmunity.Immunometabolism · 2022Article
- Birth outcomes, puberty onset, and obesity as long-term predictors of biological aging in young adulthood.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In modern societies, ageing and obesity represent medical challenges for healthcare professionals and caregivers. Obesity and ageing share common features including the related cellular and molecular pathways as well as the impacts they have as risk factors for a variety of diseases and health problems. Both of these health problems also share exercise and a healthy lifestyle as the best therapeutic options. Importantly, ageing and obesity also have common epigenetic changes (histone modification, DNA methylation, noncoding RNAs, and chromatin remodeling) that are also impacted by exercise. This suggests that epigenetic pathways are among the mechanisms via which exercise induces its benefits, including ageing and obesity improvements. Exploring these interrelations and based on the fact that both ageing and obesity represent risk factors for each other, would lead to optimizing the available therapeutic approaches towards improved obesity management and healthy ageing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.