Evidence map›Paper›PMID 34939866›Full record

ArticleTechnology in cancer research & treatment

Up-frameshift Protein 1 Promotes Tumor Progression by Regulating Apoptosis and Epithelial-Mesenchymal Transition of Colorectal Cancer.

Binlie Chen, Huaiming Wang, Danfeng Li, Xiaosheng Lin, Zhiyan Ma, Yongming Zeng

Open access · goldAbstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Exploring tyrosine kinase inhibitors for HER2-positive breast cancer: comprehensive review on a complete pharmacology-molecular mechanisms, safety profiles, and insights from preclinical and clinical studies.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Article
  3. Korean circulation journal · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Binlie Chen485866The First Affiliated Hospital of Shantou University Medical College, Shantou, People's Republic of China.
Huaiming Wang485866The First Affiliated Hospital of Shantou University Medical College, Shantou, People's Republic of China.
Danfeng Li485866The First Affiliated Hospital of Shantou University Medical College, Shantou, People's Republic of China.
Xiaosheng Lin485866The First Affiliated Hospital of Shantou University Medical College, Shantou, People's Republic of China.
Zhiyan Ma485866The First Affiliated Hospital of Shantou University Medical College, Shantou, People's Republic of China.
Yongming Zeng485866The First Affiliated Hospital of Shantou University Medical College, Shantou, People's Republic of China.ORCID 0000-0001-6704-1403
Shantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biomarkers, TumorGene Expression Regulation, NeoplasticAdultAgedApoptosisCell Line, TumorColorectal NeoplasmsDisease ProgressionDNA DamageEpithelial-Mesenchymal TransitionFemaleGene Knockdown TechniquesHumansImmunohistochemistryMaleMiddle AgedBiomarkers, TumorRNA HelicasesTrans-ActivatorsUPF1 protein, humanapoptosiscolorectal cancerDNA damageepithelial–mesenchymal transitionup-frameshift protein 1

Identifiers

PMID34939866
PMCPMC8721398
OpenAlexW4200572597

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.