Evidence map›Paper›PMID 34939692›Full record

ReviewFASEB journal : official publication of the Federation of American Societies for Experimental Biology2022

Reviving Cav1.2 as an attractive drug target to treat bladder dysfunction.

Weiqun Yu

Open access · greenAbstract readReview
In one paragraph

Review in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Antibiotics (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Weiqun YuDepartment of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachuesetts, USA.
Harvard University · US

Funding

Role of Ectonucleotidase in Voiding Function and DysfunctionR01DK126674 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI YU, WEIQUN · 2021 to 2024
$1.5M
Role of Insulin Receptor-mediated Signaling In Underactive BladderR21AG064633 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI YU, WEIQUN · 2019 to 2020
$481k
Targeting Cav1.2 to treat Ketamine-Induced PathologyU18DA052346 · NIDA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI YU, WEIQUN · 2020 to 2020
$263k
NIA NIH HHS R21 AG064633NIDA NIH HHS U18 DA052346NIDDK NIH HHS R01 DK126674
6 · The paper itself

Abstract

Inhibition of bladder contraction with antimuscarinics is a common approach to treat bladder hyperactivity, and the L-type voltage-gated calcium channel α

Indexed as

CystitisDrug Delivery SystemsUrinary Bladder, OveractiveAnimalsCalcium Channel BlockersCalcium Channels, L-TypeHumansKetamineCACNA1C protein, humanCalcium Channel BlockersCalcium Channels, L-TypeKetaminecalcium channel blockersoveractive bladdersmooth muscle

Identifiers

PMID34939692
PMCPMC9841550
OpenAlexW4200291424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.