Evidence map›Paper›PMID 34939663›Full record

ReviewThe British journal of dermatology2022

The biological basis of disease recurrence in psoriasis: a historical perspective and current models.

Lluís Puig, Antonio Costanzo, Ernesto J Muñoz-Elías, Maria Jazra, Sven Wegner, Carle F Paul, Curdin Conrad

Open access · hybridAbstract readReview
In one paragraph

Review in The British journal of dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

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  16. Therapeutic effect ofFrontiers in pharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 6 countries.

Lluís PuigDepartment of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.ORCID 0000-0001-6083-0952
Antonio CostanzoUnit of Dermatology, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.
Ernesto J Muñoz-ElíasDepartment of Immunology - Translational Biology, Biomarkers & Early Development, Janssen Research & Development, CA/Spring House, La Jolla, PA, USA.
Maria JazraMedical Affairs, Janssen-Cilag, Paris, France.
Sven WegnerMedical Affairs, Janssen-Cilag GmbH, Neuss, Germany.
Carle F PaulDepartment of Dermatology, Hôpital Larrey, CHU Toulouse, Toulouse, France.ORCID 0000-0003-0165-5263
Curdin ConradDepartment of Dermatology, University Hospital CHUV, Lausanne, Switzerland.
Hôpital Larrey · FRHospital de Sant Pau · ESHumanitas University · ITJanssen (France) · FRJanssen (Germany) · DEJanssen (United States) · USUniversity Hospital of Lausanne · CH

Funding

Janssen Pharmaceutica NV
6 · The paper itself

Abstract

A key challenge in psoriasis therapy is the tendency for lesions to recur in previously affected anatomical locations after treatment discontinuation following lesion resolution. Available evidence supports the concept of a localized immunological 'memory' that persists in resolved skin after complete disappearance of visible inflammation, as well as the role of a specific subpopulation of T cells characterized by the dermotropic CCR4

Indexed as

Interleukin-17PsoriasisHumansInterleukin-23SkinTh17 CellsInterleukin-17Interleukin-23

Identifiers

PMID34939663
PMCPMC9374062
OpenAlexW4200171094

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.