Evidence map›Paper›PMID 34939236›Full record

ArticleNMR in biomedicine2022

Learning-based optimization of acquisition schedule for magnetization transfer contrast MR fingerprinting.

Beomgu Kang, Byungjai Kim, HyunWook Park, Hye-Young Heo

Abstract read
In one paragraph

Article in NMR in biomedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  9. Review
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  13. iScience · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Article
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  19. Article
  20. Only-train-once MR fingerprinting for BMagnetic resonance in medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Beomgu KangDepartment of Electrical Engineering, Korea Advanced Institute of Science and Technology, Guseong-dong, Yuseong-gu, Daejeon, Republic of Korea.
Byungjai KimDepartment of Electrical Engineering, Korea Advanced Institute of Science and Technology, Guseong-dong, Yuseong-gu, Daejeon, Republic of Korea.
HyunWook ParkDepartment of Electrical Engineering, Korea Advanced Institute of Science and Technology, Guseong-dong, Yuseong-gu, Daejeon, Republic of Korea.ORCID 0000-0002-4757-1922
Hye-Young HeoDivison of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0002-7297-2015

Funding

TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
Ultrafast Quantitative pH MRI for Acute Ischemic Stroke PatientsR01NS112242 · NINDS · JOHNS HOPKINS UNIVERSITY · PI HEO, HYE YOUNG · 2020 to 2024
$1.9M
Chemical Exchange Saturation Transfer MR FingerprintingR01EB029974 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI HEO, HYE YOUNG · 2021 to 2024
$1.4M
NIBIB NIH HHS P41 EB031771NIBIB NIH HHS R01 EB029974NINDS NIH HHS R01 NS112242
6 · The paper itself

Abstract

Magnetization transfer contrast MR fingerprinting (MTC-MRF) is a novel quantitative imaging method that simultaneously quantifies free bulk water and semisolid macromolecule parameters using pseudo-randomized scan parameters. To improve acquisition efficiency and reconstruction accuracy, the optimization of MRF sequence design has been of recent interest in the MRF field, but has been challenging due to the large number of degrees of freedom to be optimized in the sequence. Herein, we propose a framework for learning-based optimization of the acquisition schedule (LOAS), which optimizes RF saturation-encoded MRF acquisitions with a minimal number of scan parameters for tissue parameter determination. In a supervised learning framework, scan parameters were subsequently updated to minimize a predefined loss function that can directly represent tissue quantification errors. We evaluated the performance of the proposed approach with a numerical phantom and in in vivo experiments. For validation, MRF images were synthesized using the tissue parameters estimated from a fully connected neural network framework and compared with references. Our results showed that LOAS outperformed existing indirect optimization methods with regard to quantification accuracy and acquisition efficiency. The proposed LOAS method could be a powerful optimization tool in the design of MRF pulse sequences.

Indexed as

BrainMagnetic Resonance ImagingAlgorithmsImage Processing, Computer-AssistedNeural Networks, ComputerPhantoms, ImagingCESTdeep learningMR fingerprintingMTNOEoptimization

Identifiers

PMID34939236
PMCPMC9761585

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.