Evidence map›Paper›PMID 34938960›Full record

ArticleFASEB bioAdvances2021

The butyrophilin 1a1 knockout mouse revisited: Ablation of

Jaekwang Jeong, Anil K G Kadegowda, Thomas J Meyer, Lisa M Jenkins, Jerry C Dinan, John J Wysolmerski, Roberto Weigert, Ian H Mather

Open access · goldAbstract read
In one paragraph

Article in FASEB bioAdvances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1.Journal for immunotherapy of cancer · 2024
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jaekwang JeongDepartment of Animal and Avian Sciences University of Maryland College Park Maryland USA.
Anil K G KadegowdaDepartment of Animal and Avian Sciences University of Maryland College Park Maryland USA.
Thomas J MeyerCCR Collaborative Bioinformatics Resource National Cancer Institute National Institutes of Health Bethesda Maryland USA.
Lisa M JenkinsLaboratory of Cell Biology National Cancer Institute National Institutes of Health Bethesda Maryland USA.
Jerry C DinanLaboratory of Cell Biology National Cancer Institute National Institutes of Health Bethesda Maryland USA.
John J WysolmerskiDepartment of Internal Medicine Yale University School of Medicine New Haven Connecticut USA.
Roberto WeigertLaboratory of Cellular and Molecular Biology Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda Maryland USA.
Ian H MatherDepartment of Animal and Avian Sciences University of Maryland College Park Maryland USA.ORCID https://orcid.org/0000-0002-9351-1381
National Institutes of Health · USUniversity of Maryland, College Park · USYale University · US

Funding

PMCA2 regulates mammary gland involution and breast cancerR01HD076248 · NICHD · YALE UNIVERSITY · PI WYSOLMERSKI, JOHN J · 2014 to 2024
$4.4M
Heterodimerization of the Calcium-sensing receptor with the GabaB receptors in the breast.R01HD100468 · NICHD · YALE UNIVERSITY · PI WYSOLMERSKI, JOHN J · 2020 to 2024
$2.1M
The Mechanism of Milk Lipid SecretionR01HD048588 · NICHD · UNIV OF MARYLAND, COLLEGE PARK · PI MATHER, IAN HEYWOOD · 2006 to 2009
$1.1M
NICHD NIH HHS R01 HD048588NICHD NIH HHS R01 HD076248NICHD NIH HHS R01 HD100468
6 · The paper itself

Abstract

Butyrophilin 1A1 (BTN1A1) is implicated in the secretion of lipid droplets from mammary epithelial cells as a membrane receptor, which forms a secretion complex with the redox enzyme, xanthine oxidoreductase (XDH). The first evidence that BTN1A1 functions in this process was the generation of

Indexed as

apoptosisbutyrophilin 1a1cell deathcell renewalmilk‐lipid secretionxanthine oxidoreductase

Identifiers

PMID34938960
PMCPMC8664049
OpenAlexW3195867258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.