Evidence map›Paper›PMID 34938920›Full record

ArticleBioactive materials2022

The biological effect of recombinant humanized collagen on damaged skin induced by UV-photoaging: An

Jing Wang, He Qiu, Yang Xu, Yongli Gao, Peijie Tan, Rui Zhao, Zhanhong Liu, Yajun Tang, Xiangdong Zhu, Chongyun Bao and 3 more

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 89 citations in OpenAlex.

  1. Reduction of Ultraviolet- and Heat-Induced Aging Using Betulin-Loaded Arginine-Caprylate Self-Assembly: Randomized Double-Blind Clinical Trials.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
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  5. [Role and Potential Mechanisms of Peroxisome Proliferator-Activated Receptor α in Ultraviolet B Radiation-Induced Skin Damage].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Jing WangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China.
He QiuWest China School / Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610064, China.
Yang XuNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China.
Yongli GaoNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China.
Peijie TanWest China School / Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610064, China.
Rui ZhaoWest China School / Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610064, China.
Zhanhong LiuNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China.
Yajun TangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China.
Xiangdong ZhuNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China.
Chongyun BaoWest China School / Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610064, China.
Hang WangWest China School / Hospital of Stomatology, Sichuan University, Chengdu, Sichuan 610064, China.
Hai LinNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China.
Xingdong ZhangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan 610064, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of medical devices to repair skin damage is clinically accepted and natural polymer enjoys an important role in this field, such as collagen or hyaluronic acid, etc. However, the biosafety and efficacy of these implants are still challenged. In this study, a skin damage animal model was prepared by UV-photoaging and recombinant humanized type III collagen (rhCol III) was applied as a bioactive material to implant

Indexed as

Biological effectRecombinant collagenSafety and efficacySkin regenerationType III collagen

Identifiers

PMID34938920
PMCPMC8665261
OpenAlexW3210124477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.