Evidence map›Paper›PMID 34938915›Full record

ArticleBioactive materials2022

Enhanced bone regenerative properties of calcium phosphate ceramic granules in rabbit posterolateral spinal fusion through a reduction of grain size.

Xiangfeng Li, Quan Zhou, Yonghao Wu, Cong Feng, Xi Yang, Linnan Wang, Yumei Xiao, Kai Zhang, Xiangdong Zhu, Limin Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. A Novel Deer Antler-Inspired Bone Graft Triggers Rapid Bone Regeneration.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Calcium Phosphate-Based Biomaterials for Bone Repair.Journal of functional biomaterials · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Xiangfeng LiNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Quan ZhouDepartment of Orthopaedic Surgery, West China Hospital of Sichuan University, Chengdu, 610041, China.
Yonghao WuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Cong FengNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Xi YangDepartment of Orthopaedic Surgery, West China Hospital of Sichuan University, Chengdu, 610041, China.
Linnan WangDepartment of Orthopaedic Surgery, West China Hospital of Sichuan University, Chengdu, 610041, China.
Yumei XiaoNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Kai ZhangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Xiangdong ZhuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Limin LiuDepartment of Orthopaedic Surgery, West China Hospital of Sichuan University, Chengdu, 610041, China.
Yueming SongDepartment of Orthopaedic Surgery, West China Hospital of Sichuan University, Chengdu, 610041, China.
Xingdong ZhangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610064, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoinductivity is a crucial factor to determine the success and efficiency of posterolateral spinal fusion (PLF) by employing calcium phosphate (Ca-P) bioceramics. In this study, three kinds of Ca-P ceramics with microscale to nanoscale gain size (BCP-control, BCP-micro and BCP-nano) were prepared and their physicochemical properties were characterized. BCP-nano had the spherical shape and nanoscale gain size, BCP-micro had the spherical shape and microscale gain size, and BCP-control (BAM®) had the irregular shape and microscale gain size. The obtained BCP-nano with specific nanotopography could well regulate

Indexed as

Calcium phosphate ceramicsNanotopographyOsteogenic differentiationOsteoinductivityPosterolateral spinal fusion

Identifiers

PMID34938915
PMCPMC8665272
OpenAlexW3204270325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.