ArticleLaryngoscope investigative otolaryngology2021
Predictors of severe dysphagia following radiotherapy for head and neck cancer.
Article in Laryngoscope investigative otolaryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Prognostic models for radiation-induced complications after radiotherapy in head and neck cancer patients.The Cochrane database of systematic reviews · 2025Pooled it
- Preventing radiation-induced dysphagia and trismus in head and neck cancer-A randomized controlled trial.Head & neck · 2025Trial
- The Role of Saliva in Swallowing: A Systematic Review.Dysphagia · 2026Review
- Evaluation of Swallowing Function and Aspiration in Newly Diagnosed Head and Neck Cancer Patients.Dysphagia · 2026Article
- CT-Defined Low Skeletal Muscle Mass Predicts Early Swallowing and Quality-of-Life Recovery After Head-and-Neck Oncologic Reconstruction.Diagnostics (Basel, Switzerland) · 2026Article
- Analysis of clinical efficacy and quality of life in hypopharyngeal cancer patients undergoing laryngeal-preserving surgery.Frontiers in oncology · 2026Article
- Analysis of preoperative swallowing function in head and neck cancer patients based on fiberoptic endoscopic evaluation of swallowing (FEES): a cross-sectional study.BMC oral health · 2025Article
- Deep learning NTCP model for late dysphagia after radiotherapy for head and neck cancer patients based on 3D dose, CT and segmentations.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2025Article
- Validation of the Swedish Eating Assessment Tool, S-EAT-10, for patients with head and neck cancer.Scientific reports · 2025Article
- Radiation-Induced Fibrosis in Head and Neck Cancer: Challenges and Future Therapeutic Strategies for Vocal Fold Treatments.Cancers · 2025Review
- Prospective study on health-related quality of life, oral mucositis and oral health on during treatment of head and neck cancer.BMC oral health · 2024Article
- Profiling of swallowing function in head and neck cancer patients prior to radiation therapy-Findings from a tertiary hospital in South India.Preventive medicine reports · 2024Article
- Analysis of swallowing and voice-related quality of life in patients after supracricoid partial laryngectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Exploring predictors of dysphagia in survivors of head and neck cancer: A cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Predictive Factors for Chemoradiation-Induced Oral Mucositis and Dysphagia in Head and Neck Cancer: A Scoping Review.Cancers · 2023Article
- Chemoradiotherapy with 3-weekly CDDP 80 mg/mFrontiers in surgery · 2022Article
- Predictors of severe dysphagia following radiotherapy for head and neck cancer.Laryngoscope investigative otolaryngology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate if severe dysphagia following radiotherapy for head and neck cancer (HNC) could be predicted by patient and tumor characteristics, feeding tube use, weight factors, jaw opening function, and saliva secretion.
methodsData was collected from 94 HNC patients 6 to 36 months post radiotherapy. Swallowing function was assessed by videofluroscopy (VFS). Severe dysphagia was defined by Penetration Aspiration Scale (PAS) as PAS≥5 or a total score ≤60 on the M. D. Anderson Dysphagia Inventory (MDADI).
resultsThirty-three patients (35%) had PAS ≥5 and 19 (20%) a MDADI ≤60, that is, presented with severe dysphagia. Univariable logistic regression analysis (UVA) gave that tumor of the tonsil, overweight at time of VFS and each unit increase in Body Mass Index (BMI) predicted less risk of PAS ≥5. Dependency of feeding tube at time of VFS and each month's continued use and weight loss ≥7.5% since treatment to time of VFS predicted increased risk of PAS ≥5. Predictive variables from the UVA of PAS ≥5 (tumor of the tonsil, overweight, and total duration of feeding tube), were analyzed by multivariate logistic regression analysis. All retained power as independent predictors. UVA for MDADI showed that use of feeding tube at time of VFS predicted MDADI ≤60 with the risk increasing each month. Each increasing unit of BMI decreased risk of MDADI ≤60.
conclusionLong time users of feeding tube and higher weight-loss are at risk of severe dysphagia. This makes collaboration between professionals working with dysphagia an important step in detecting severe dysphagia.Level of Evidence: 3.
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