ArticleLaryngoscope investigative otolaryngology2021
Roles of skull base surgery and particle radiotherapy for orbital malignant tumors involving the skull base.
Article in Laryngoscope investigative otolaryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Treatment of Skull Base Diseases: A Multidisciplinary Challenge.Journal of clinical medicine · 2023Article
- Roles of skull base surgery and particle radiotherapy for orbital malignant tumors involving the skull base.Laryngoscope investigative otolaryngology · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
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Abstract
purposeTo investigate the oncological outcomes of orbital malignant tumors invading the skull base.
methodsA retrospective analysis was conducted on 16 patients with orbital malignant tumors invading the skull base. Eleven patients were treated with skull base surgery, four patients were treated with particle therapies, and one patient was treated with chemoradiotherapy (CRT) as initial treatment.
resultsThe most frequent histological type was adenoid cystic carcinoma in seven patients, followed by squamous cell carcinoma in two patients. Local recurrence occurred in two of the six surgically treated patients who did not receive postoperative radiotherapy (RT) or CRT. One of them was successfully salvaged by RT, and the other died of disease. With a median follow-up of 24 months, the 2-year overall, local control, and disease-free survival rates of all patients were 82.5%, 87.5%, and 59%, respectively.
conclusionsPatients with positive surgical margins were at risk of local recurrence. Postoperative RT should be considered for all surgically treated patients.Level of Evidence: 4.
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