Evidence map›Paper›PMID 34938799›Full record

ReviewERJ open research2021

Home monitoring of physiology and symptoms to detect interstitial lung disease exacerbations and progression: a systematic review.

Malik A Althobiani, Rebecca A Evans, Jaber S Alqahtani, Abdulelah M Aldhahir, Anne-Marie Russell, John R Hurst, Joanna C Porter

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Differentiating the start of an exacerbation from day-to-day variation in people with COPD: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Malik A AlthobianiUCL Respiratory, University College London, London, UK.ORCID https://orcid.org/0000-0002-2230-5708
Rebecca A EvansUniversity College London Hospitals NHS Foundation Trust, London, UK.
Jaber S AlqahtaniUCL Respiratory, University College London, London, UK.ORCID https://orcid.org/0000-0003-1795-5092
Abdulelah M AldhahirRespiratory Care Dept, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia.
Anne-Marie RussellUniversity of Exeter College of Medicine and Health, Exeter, UK.ORCID https://orcid.org/0000-0002-0468-3537
John R HurstUCL Respiratory, University College London, London, UK.ORCID https://orcid.org/0000-0002-7246-6040
Joanna C PorterUCL Respiratory, University College London, London, UK.ORCID https://orcid.org/0000-0002-7307-169X
University College London · GBJazan University · SAKing Abdulaziz University · SAPrince Sultan Military College of Health SciencesUniversity College London Hospitals NHS Foundation Trust · GBUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute exacerbations (AEs) and disease progression in interstitial lung disease (ILD) pose important challenges to clinicians and patients. AEs of ILD are variable in presentation but may result in rapid progression of ILD, respiratory failure and death. However, in many cases AEs of ILD may go unrecognised so that their true impact and response to therapy is unknown. The potential for home monitoring to facilitate early, and accurate, identification of AE and/or ILD progression has gained interest. With increasing evidence available, there is a need for a systematic review on home monitoring of patients with ILD to summarise the existing data. The aim of this review was to systematically evaluate the evidence for use of home monitoring for early detection of exacerbations and/or progression of ILD.

methodWe searched Ovid-EMBASE, MEDLINE and CINAHL using Medical Subject Headings (MeSH) terms in accordance with the PRISMA guidelines (PROSPERO registration number CRD42020215166).

results13 studies involving 968 patients have demonstrated that home monitoring is feasible and of potential benefit in patients with ILD. Nine studies reported that mean adherence to home monitoring was >75%, and where spirometry was performed there was a significant correlation (r=0.72-0.98, p<0.001) between home and hospital-based readings. Two studies suggested that home monitoring of forced vital capacity might facilitate detection of progression in idiopathic pulmonary fibrosis.

conclusionDespite the fact that individual studies in this systematic review provide supportive evidence suggesting the feasibility and utility of home monitoring in ILD, further studies are necessary to quantify the potential of home monitoring to detect disease progression and/or AEs.

Identifiers

PMID34938799
PMCPMC8685510
OpenAlexW3207134423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.