Evidence map›Paper›PMID 34938672›Full record

ArticleFrontiers in cellular and infection microbiology2021

Bladder Exposure to

Valerie P O'Brien, Amanda L Lewis, Nicole M Gilbert

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Strain-level differences inbioRxiv : the preprint server for biology · 2025
    Article
  4. Review
  5. Controversy and multiple roles of the solitary nucleus receptor Nur77 in disease and physiology.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Immune defenses in the urinary tract.Trends in immunology · 2023
    Review
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Valerie P O'BrienHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.
Amanda L LewisDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, San Diego, CA, United States.
Nicole M GilbertDepartment of Pediatrics, Division of Infectious Diseases, Washington University in St. Louis School of Medicine, St. Louis, MO, United States.
Fred Hutch Cancer Center · USUniversity of California, San Diego · USWashington University in St. Louis · US

Funding

ROLES OF SIALIDASE IN G. VAGINALIS-HOST INTERACTIONS DURING BACTERIAL VAGINOSISR01AI114635 · NIAID · WASHINGTON UNIVERSITY · PI LEWIS, AMANDA L., LEWIS, WARREN G · 2015 to 2025
$5.9M
ANIMAL SUPPORT SPACE FOR NEUROSCIENCEC06RR015502 · NCRR · WASHINGTON UNIVERSITY · PI CICERO, THEODORE J · 2000 to 2000
$2.0M
Role of Gardnerella vaginalis in the Urinary TractK01DK110225 · NIDDK · WASHINGTON UNIVERSITY · PI GILBERT, NICOLE MARIE · 2017 to 2021
$560k
ROLE OF GBS CAPSULE IN ASCENDING E. COLI UTI & UROSEPSIS IN AGED MULTIPAROUS MICER21DK092586 · NIDDK · WASHINGTON UNIVERSITY · PI LEWIS, AMANDA L. · 2012 to 2013
$409k
Roles of vaginal bacteria in bladder exfoliation and recurrent UTIR21AI152049 · NIAID · WASHINGTON UNIVERSITY · PI LEWIS, AMANDA L. · 2020 to 2021
$393k
NCRR NIH HHS C06 RR015502NIAID NIH HHS R01 AI114635NIAID NIH HHS R21 AI152049NIDDK NIH HHS K01 DK110225NIDDK NIH HHS R21 DK092586
6 · The paper itself

Abstract

Recurrent urinary tract infections (rUTI) are a costly clinical problem affecting millions of women worldwide each year. The majority of rUTI cases are caused by uropathogenic

Indexed as

Escherichia coli InfectionsUrinary Tract InfectionsUropathogenic Escherichia coliAnimalsFemaleGardnerellaMiceUrinary Bladderbacterial vaginosis (BV)bladderimmediate early gene expressionNur77orphan nuclear receptor 4A1 (NR4A1)RNA-seq - RNA sequencingurinary microbiomeurinary tract infection (UTI)

Identifiers

PMID34938672
PMCPMC8685330
OpenAlexW4200568736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.