Evidence map›Paper›PMID 34938668›Full record

ReviewFrontiers in cellular and infection microbiology2021

Prospects of Inhaled Phage Therapy for Combatting Pulmonary Infections.

Xiang Wang, Zuozhou Xie, Jinhong Zhao, Zhenghua Zhu, Chen Yang, Yi Liu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Phage therapy againstFrontiers in microbiology · 2026
    Review
  4. Article
  5. Review
  6. Microorganisms · 2025
    Review
  7. Article
  8. Efficacy of Three Kayviruses AgainstAntibiotics (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Diversification ofMicroorganisms · 2024
    Article
  15. Aerosolic Application of Phages AgainstPHAGE (New Rochelle, N.Y.) · 2024
    Article
  16. Review
  17. Phage therapy: breathing new tactics into lower respiratory tract infection treatments.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiang WangDepartment of Pulmonary and Critical Care Medicine, The Second People's Hospital of Kunming, Kunming, China.
Zuozhou XieDepartment of Pulmonary and Critical Care Medicine, The Second People's Hospital of Kunming, Kunming, China.
Jinhong ZhaoDepartment of Pulmonary and Critical Care Medicine, The Second People's Hospital of Kunming, Kunming, China.
Zhenghua ZhuDepartment of Pulmonary and Critical Care Medicine, The Second People's Hospital of Kunming, Kunming, China.
Chen YangDepartment of Pulmonary and Critical Care Medicine, The Second People's Hospital of Kunming, Kunming, China.
Yi LiuDepartment of Pulmonary and Critical Care Medicine, The Second People's Hospital of Kunming, Kunming, China.
Xian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With respiratory infections accounting for significant morbidity and mortality, the issue of antibiotic resistance has added to the gravity of the situation. Treatment of pulmonary infections (bacterial pneumonia, cystic fibrosis-associated bacterial infections, tuberculosis) is more challenging with the involvement of multi-drug resistant bacterial strains, which act as etiological agents. Furthermore, with the dearth of new antibiotics available and old antibiotics losing efficacy, it is prudent to switch to non-antibiotic approaches to fight this battle. Phage therapy represents one such approach that has proven effective against a range of bacterial pathogens including drug resistant strains. Inhaled phage therapy encompasses the use of stable phage preparations given

Indexed as

Bacterial InfectionsBacteriophagesPhage TherapyPneumoniaBacteriaHumansantimicrobial resistanceinhaled phage therapymulti-drug resistancenebulizerpulmonary infection

Identifiers

PMID34938668
PMCPMC8685529
OpenAlexW4200500444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.