Evidence map›Paper›PMID 34938603›Full record

ArticleMolecular therapy. Nucleic acids2022

circRNA-0002109 promotes glioma malignant progression via modulating the miR-129-5P/EMP2 axis.

Haibin Xia, Boyang Liu, Nanxiang Shen, Jinhua Xue, Siyu Chen, Hongbo Guo, Xiaozhong Zhou

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Haibin XiaInstitute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University, 250 Chang-gang East Road, Guangzhou 510260, China.
Boyang LiuNeurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Nanxiang ShenInstitute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University, 250 Chang-gang East Road, Guangzhou 510260, China.
Jinhua XueDepartment of Physiology, School of Basic Medical Sciences, Gannan Medical University, Ganzhou 341000, China.
Siyu ChenInstitute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University, 250 Chang-gang East Road, Guangzhou 510260, China.
Hongbo GuoNeurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Xiaozhong ZhouTrauma Center, First Affiliated Hospital of Gannan Medical University, Ganzhou 341000, China.
Second Affiliated Hospital of Guangzhou Medical University · CNZhujiang Hospital · CNFirst Affiliated Hospital of Gannan Medical University · CNGannan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma is a common intracranial malignant tumor with high mortality and high recurrence rate. In recent years, increasing evidence has demonstrated that circular RNAs (circRNAs) are potential biomarkers and therapeutic targets for many tumors. However, the role of circRNAs in glioma remains unclear. In this study, we found that circRNA-0002109 was highly expressed in glioma tissues and cell lines. Downregulation of circRNA-0002109 expression inhibited the proliferation, migration, and invasion of glioma cells and inhibited the malignant progression of tumors

Indexed as

ceRNAcircRNA-0002109EMP2gliomamiR-129-5P

Identifiers

PMID34938603
PMCPMC8646083
OpenAlexW3217649437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.