Evidence map›Paper›PMID 34938575›Full record

ArticleGlobal challenges (Hoboken, NJ)2021

Optimization of Quercetin-Assisted Silver Nanoparticles Synthesis and Evaluation of Their Hemocompatibility, Antioxidant, Anti-Inflammatory, and Antibacterial effects.

Azam Chahardoli, Pouria Hajmomeni, Mahnaz Ghowsi, Farshad Qalekhani, Yalda Shokoohinia, Ali Fattahi

Abstract read
In one paragraph

Article in Global challenges (Hoboken, NJ), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Synthesis of AgJournal of functional biomaterials · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Antibiotics (Basel, Switzerland) · 2023
    Article
  14. Biosynthesis of Silver Nanoparticles UsingMolecules (Basel, Switzerland) · 2023
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Azam ChahardoliDepartment of Biology Faculty of Science Razi University Kermanshah 6714414971 Iran.ORCID https://orcid.org/0000-0001-9591-1170
Pouria HajmomeniPharmaceutical Sciences Research Center Health Institute Kermanshah University of Medical Sciences Kermanshah 6734667149 Iran.
Mahnaz GhowsiDepartment of Biology Faculty of Science Razi University Kermanshah 6714414971 Iran.
Farshad QalekhaniPharmaceutical Sciences Research Center Health Institute Kermanshah University of Medical Sciences Kermanshah 6734667149 Iran.
Yalda ShokoohiniaPharmaceutical Sciences Research Center Health Institute Kermanshah University of Medical Sciences Kermanshah 6734667149 Iran.
Ali FattahiPharmaceutical Sciences Research Center Health Institute Kermanshah University of Medical Sciences Kermanshah 6734667149 Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, different effective parameters (temperature, reaction time, and pH) on the synthesis of quercetin-assisted silver nanoparticles (QE-AgNPs) are optimized. These biogenic NPs are characterized by different physico-chemical analyses, including transmission electron microscopy, X-ray diffraction, Fourier transform infrared (FTIR) spectroscopy, and UV-visible spectroscopy. In addition, the biological properties of QE-AgNPs are evaluated through antioxidant, antimicrobial, anti-inflammatory, hemolysis, and coagulation time assays. The formation of QE-AgNPs is affected by different parameters. The optimum condition for the synthesis of QE-AgNPs is attained at 70 °C and pH 7. Prepared QE-AgNPs show a spherical shape with a crystalline nature and an average particle size of 20 ± 3.6 nm. The role of QE as a reducing and capping agent in the preparation process of QE-AgNPs is demonstrated using FTIR analysis. These NPs with excellent antioxidant activity (82.3% at a concentration of 400 µg mL

Indexed as

anti‐inflammatory activityantimicrobial effectcoagulation timehemolysisQE‐AgNPsquercetin

Identifiers

PMID34938575
PMCPMC8671616

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.