Evidence map›Paper›PMID 34938570›Full record

ArticleHealthcare technology letters2021

Retrospective validation of a machine learning clinical decision support tool for myocardial infarction risk stratification.

Saarang Panchavati, Carson Lam, Nicole S Zelin, Emily Pellegrini, Gina Barnes, Jana Hoffman, Anurag Garikipati, Jacob Calvert, Qingqing Mao, Ritankar Das

Open access · goldAbstract read
In one paragraph

Article in Healthcare technology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Saarang PanchavatiDivision of Data Science Dascena, Inc. Houston Texas USA.
Carson LamDivision of Data Science Dascena, Inc. Houston Texas USA.
Nicole S ZelinDivision of Data Science Dascena, Inc. Houston Texas USA.
Emily PellegriniDivision of Data Science Dascena, Inc. Houston Texas USA.ORCID https://orcid.org/0000-0001-7614-9299
Gina BarnesDivision of Data Science Dascena, Inc. Houston Texas USA.
Jana HoffmanDivision of Data Science Dascena, Inc. Houston Texas USA.
Anurag GarikipatiDivision of Data Science Dascena, Inc. Houston Texas USA.
Jacob CalvertDivision of Data Science Dascena, Inc. Houston Texas USA.
Qingqing MaoDivision of Data Science Dascena, Inc. Houston Texas USA.
Ritankar DasDivision of Data Science Dascena, Inc. Houston Texas USA.
Dascena (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis and appropriate intervention for myocardial infarction (MI) are time-sensitive but rely on clinical measures that can be progressive and initially inconclusive, underscoring the need for an accurate and early predictor of MI to support diagnostic and clinical management decisions. The objective of this study was to develop a machine learning algorithm (MLA) to predict MI diagnosis based on electronic health record data (EHR) readily available during Emergency Department assessment. An MLA was developed using retrospective patient data. The MLA used patient data as they became available in the first 3 h of care to predict MI diagnosis (defined by International Classification of Diseases, 10th revision code) at any time during the encounter. The MLA obtained an area under the receiver operating characteristic curve of 0.87, sensitivity of 87% and specificity of 70%, outperforming the comparator scoring systems TIMI and GRACE on all metrics. An MLA can synthesize complex EHR data to serve as a clinically relevant risk stratification tool for MI.

Identifiers

PMID34938570
PMCPMC8667565
OpenAlexW3197051133

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.